Ethanol-induced changes in lipid peroxidation and glutathione content in rat brain |
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| Authors: | M Uysal G Kutalp G Ozdemirler G Ayka? |
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| Affiliation: | Department of Biochemistry, Istanbul Faculty of Medicine, University of Istanbul, Capa, Turkey. |
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| Abstract: | The effect of acute and chronic ethanol administration on brain lipid peroxide and glutathione levels was investigated in rats. Acute ethanol administration (5 g/kg, i.p.) led to an increase in lipid peroxide levels and a decrease in glutathione levels in whole brain homogenates without cerebellum. However, there was no change in brain lipid peroxide and glutathione levels of rats chronically treated with ethanol. |
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