A case of multiple liver metastases of gastric cancer successfully treated by combination chemotherapy of S-1 and paclitaxel |
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Authors: | Yasuda Seiichi Komatsubara Takashi Inamoto Susumu Lee Jeong Teramura Yasufumi Hashida Shuhei Akamatsu Shin |
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Affiliation: | Dept. of Surgery, Hikone Municipal Hospital, Japan. |
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Abstract: | A 54-year-old man underwent distal gastrectomy for early gastric cancer in September 2002. CT performed 6 months after the operation revealed liver metastases, and they were resected. Hepatic arterial infusion therapy of 5-FU was performed; however, multiple liver metastases appeared in October 2003. We added arterial infusion of CDDP to 5-FU, but liver metastases increased. We then applied a combination chemotherapy of S-1 and paclitaxel from February 2004. Subsequently, stable disease continued, and after 67 courses of S-1 plus paclitaxel, we changed the administration to S-1 alone from August 2009. After that, liver metastases did not increase, so we discontinued chemotherapy on August 2010, followed by observation. Progression of liver metastases has not been to date. |
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