基底动脉尖综合征63例临床分析

目的 探讨基底动脉尖综合征（TOBS）的临床及影像学特征。方法 对63例TOBS患者的临床表现及影像学资料进行回顾性分析。结果 栓塞和血栓形成是TOBS的主要病因，眩晕、意识障碍、眼球运动障碍、瞳孔异常、偏盲等是该病最常见的临床表现，以丘脑或中脑为核心合并其他部位梗塞是该病影像学重要特征。结论TOBS同时具有幕上及幕下多处梗塞，并发症多，预后差，早期行MRI检查可明确诊断，全面综合治疗可改善预后。

Clinical analysis of 63 patients with top of the basilar artery syndrome

Objective To study the clinical and neuroimaging features of top of the basilar artery syndrome(TOBS).Methods The clinical and neuroimaging features of 63 cases with TOBS were analyzed retrospectively.Results Main causes of TOBS were atherosclerosis and embolisms.Vertigo and disturbance of consciousness and movement of the eye-ball,abnormality of pupils,partial blindness were the main clinical features.The most important imageologic feature of TOBS was infarction of thalami or midbrain,which was frequently complicating with infarction in other locations.Conclusion TOBS has simultaneously more than two infarction lesions,either superior or inferior tentorium of cerebellum with many complications and poor prognosis.MRI is more sensitive than CT.Early MRI examination,systemic and comprehansive treatment may improve the prognosis of the TOBS patients.