| 半导体激光诱发脉络膜新生血管的研究 |
| |
| 引用本文： | 刘安,曹明芳,金威尔.半导体激光诱发脉络膜新生血管的研究[J].福建中医学院学报,2008,18(3):54-58. |
| |
| 作者姓名： | 刘安 曹明芳 金威尔 |
| |
| 作者单位： | 福建中医学院附属人民医院,福建,福州,350004 |
| |
| 基金项目： | 国家中医药管理局科研项目 |
| |
| 摘 要： | 目的研究脉络膜新生血管的发生机制。方法用半导体激光建立脉络膜新生血管的动物模型，造模后1、2、3、4、8周行荧光素眼底血管造影检查，8周行光学相干断层扫描检查，HE染色观察。结果半导体激光造模后2周，荧光素眼底血管造影时开始渗漏，4周时渗漏达到高峰，8周时趋于稳定。造模后8周，光学相干断层扫描检查、HE染色可见脉络膜新生血管。结论半导体激光可诱导脉络膜新生血管动物模型，该模型可作为人类脉络膜新生血管模型进行实验研究。
|
| 关 键 词： | 脉络膜 新生血管 荧光素眼底血管造影 光学相干断层扫描 |
Experimental Study of Choroidal Neovascularization Induced by Semiconductor Laser |
| |
| LIU An,CAO Ming-fang,JIN Wei-er.Experimental Study of Choroidal Neovascularization Induced by Semiconductor Laser[J].Journal of Fujian College of Traditional Chinese Medicine,2008,18(3):54-58. |
| |
| Authors: | LIU An CAO Ming-fang JIN Wei-er |
| |
| Institution: | LIU An, CAO Ming-fang, JIN Wei-er(The First Affiliated Hospital, FUTCM, Fuzhou, Fujian 350004, China) |
| |
| Abstract: | Objective To study the pathogenesis of choroidal neovascularization (CNV).Methods CNV animal models were induced with semiconductor laser,then the fundus fluorescein angiography (FFA) examination occurred after 1,2,3,4 and 8 week respectively,the optical coherence tomography (OCT) examination occurred just before euthanasia and tissue was processed for hematoxylin eosin stain in 8th week. Results The leakage of CNV was firstly observed in 2nd week by FFA,the highest rate was observed on week 4 till to week 8.CNV was confirmed by OCT and hematoxylin eosin stain.Conclusion The model induced by semiconductor laser can be used as an animal model for experimental study of CNV. |
| |
| Keywords: | choroidal neovascularization fundus fluorescein angiography optical coherence tomography |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
