| 大鼠肾囊丹参肾内转运动态的研究 |
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| 引用本文： | 田松,高沪滨,陶放,于仲元. 大鼠肾囊丹参肾内转运动态的研究[J]. 中国中西医结合杂志, 1993, 13(11): 670-671,645,646 |
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| 作者姓名： | 田松 高沪滨 陶放 于仲元 |
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| 作者单位： | 北京医科大学人民医院肾内科，北京医科大学人民医院肾内科，北京医科大学人民医院肾内科，北京医科大学人民医院肾内科 北京 100044，北京 100044，北京 100044，北京 100044 |
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| 摘 要： | 应用高效液相色谱技术检测了大鼠肾囊注射丹参后不同时间肾脏组织和血液中丹参的浓度。结果显示肾脏组织中丹参浓度明显高于血中丹参浓度，２４ｈ达高峰，至４８ｈ仍维持在较高水平，且不依赖于血中丹参浓度变化。表明肾囊中丹参可被动转运至肾脏，形成肾脏高浓度区。以此可作为应用肾囊药物注射治疗多种肾脏疾病的基础。
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| 关 键 词： | 肾囊注射 丹参 高效液相色谱 |
Transportation Trends after Rat Renal Intracapsular Injection of Salvia Miltiorrhizae |
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| Tian Song,Gao Hu-bin,Tao Fang. Transportation Trends after Rat Renal Intracapsular Injection of Salvia Miltiorrhizae[J]. Chinese journal of integrated traditional and Western medicine, 1993, 13(11): 670-671,645,646 |
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| Authors: | Tian Song Gao Hu-bin Tao Fang |
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| Abstract: | The concentration of Salvia miltiorrhizae (SM) was detected at different time after renalintracapsular injection in S. D rats. It showed that SM concentration was higher in kidney than inplasma (P< 0.05). SM concentration in kidney increased gradually, it reached the peak at 24 hour andstill remained in higher level at 48 hour. The SM injected in renal capsule could be passivelytransported to renal tissue and maintained at a high level. This result demonstrated that renal intracapsular injection could be applied as an important therapeutical method for different renaldisease. |
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| Keywords: | renal intracapsular injection Salvia miltiorrhizae |
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