Adult onset Krabbe's leukodystrophy: a report of 2 cases |
| |
Authors: | M. Turazzini A. Beltramello R. Bassi R. Del Colle M. Silvestri |
| |
Affiliation: | From the Division of Neurology, Legnago;Institute of Radiology, University of Verona, Italy |
| |
Abstract: | Krabbe's disease with adult onset is rare; neurological symptoms begin in childhood or at a juvenile age. Two brothers with adult onset of the disease are here reported; 1 sibling developed parapareto-ataxic gait while the other was asymptomatic. Magnetic resonance imaging showed areas of demyelination in the white matter of the brain, while nerve conduction was completely normal. In both patients deficiency of galactosylceramide beta-salactosidase was comnarable to the infantile form. |
| |
Keywords: | Krabbe's disease adult onset magnetic resonance imaging (MRI) |
|