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光茎大黄化学成分研究
引用本文:魏玉辉,武新安,张承忠,李冲.光茎大黄化学成分研究[J].中药材,2005,28(8):658-660.
作者姓名:魏玉辉  武新安  张承忠  李冲
作者单位:1. 兰州大学第一医院药剂科,甘肃兰州730000
2. 兰州大学药学院,甘肃兰州730000
摘    要:目的:对光茎大黄根部的化学成分进行研究.方法:采用硅胶柱层析、重结晶、MS、1HNMR、13CNMR等技术进行分离、结构鉴定.结果:从该植物中分离并鉴定了七个化合物,分别是:正二十六烷酸(n-hexacosnic acid,Ⅰ),棕榈酸(palmitic acid,Ⅱ),胡萝卜甙(daucosterol,Ⅲ),大黄酚甲醚(chrysophanol-8-Me ether,Ⅳ),ω羟基大黄素(citreorosein,Ⅴ),大黄酚-8-O-葡萄糖甙(chrysophanol-8-O-β-D-glucopyranoside,Ⅵ)和2,5-二甲基-7-甲氧基色原酮(2,5-dimethyl-7-methoxychromone Ⅶ).结论:该七个化合物均为首次从该植物中分离得到.

关 键 词:光茎大黄  蒽醌类  色原酮
收稿时间:2005-03-21
修稿时间:2005年3月21日

Studies on Chemical Constituents of Rheum glabricaule
Wei Yuhui,WU Xin'an,Zhang Chengzhong,Li Chong.Studies on Chemical Constituents of Rheum glabricaule[J].Jorunal of Chinese Medicinal Materials,2005,28(8):658-660.
Authors:Wei Yuhui  WU Xin'an  Zhang Chengzhong  Li Chong
Institution:Department of Pharmacy, First Hospital of Lanzhou University, Lanzhou.
Abstract:OBJECTIVE: To study the chemical Constituents in the root of Rheum glabricaule. METHODS: Compounds were isolated by various column chromatographies with sillica gel. Their structures were identified by spectral analysis (MS, 1HNMR, 13 CNMR) and chemical evidences. RESULTS: Seven compounds were isolated from this plant, including n-hexacosnic acid (I), palmitic acid (II), daucosterol (III), chrysophanol-8-Me ether (IV), citreorosein (V), chrysophanol 8-O-beta-D-glucopyranoside (VI) and 2,5-dimethyl-7-methoxychromone (VII). CONCLUSION: All above compounds are obtained from this plant for the first time.
Keywords:Rheum glabricaule  Anthrapuinones  Chromone
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