安心康滴丸治疗病毒性心肌炎的实验研究*

目的:评价安心康滴丸治疗病毒性心肌炎的效果。方法:采用注射柯萨奇病毒感染Balb/c小鼠建立病毒性心肌炎的动物模型,比较安心康滴丸(灌胃给药,1．1,2．2和3．3 g·kg~(-1),qd,持续14 d)对模型动物的心肌病理学改变、心肌病毒滴度、血清肌钙蛋白和血清肌酸激酶的影响。结果:安心康滴丸3．3和2．2 g·kg~(-1)组能有效地减轻心肌中的病理改变、降低心肌中的病毒滴度和血清肌酸激酶的含量,同时安心康滴丸高、中、低三个剂量组均能降低血清肌钙蛋白的含量。结论:安心康滴丸对小鼠病毒性心肌炎具有显著的疗效。

Experimental research on the therapy of viral myocarditis with Anxinkang drop pills

Objective:To evaluate therapy effects of Anxinkang drop pills on viral myocarditis. Methods:The Balb/c mice were infected with CVB_3.Then we evaluate the effects of Anxinkang drop pills on the myocardium pathobiology change,cardiac muscie virus titer,serum troponin and CK.Result: The high and middle dose group could effectivity rehabilitate myocardium pathobiology change,reduce the cardiac muscie virus titer and CK.All dose groups could reduce serum troponin.Conclusion:Anxin- kang drop pills has therapeutic effect on viral myocarditis.