子宫腺肌病与子宫肌瘤患者的血清CA125测定

目的　探讨血清CA12 5测定对子宫腺肌病及子宫肌瘤的诊断价值。方法　采用放射免疫方法 (IRMA)对 10 1例子宫腺肌病 (腺肌病组 ) ,374例子宫肌瘤 (肌瘤组 ) ,32例子宫肌瘤合并腺肌病 (合并组 )的患者血清CA12 5进行测定。结果　三组血清CA12 5阳性率分别为 88.12 % ,12 .30 % ,87.5 0 % ,均值分别为 118.37± 78.2 1kU /L ,17.45± 14 .36kU/L ,10 6 .49± 6 3.91kU /L ,肌瘤组血清CA12 5均值及阳性率均明显低于另两组 ,差异有显著性 (P <0 .0 5 ) ,腺肌病组、合并组间的血清CA12 5均值及阳性率差异无显著性 (P >0 .0 5 )。结论　血清CA12 5测定对子宫腺肌病有辅助诊断价值 ,对子宫腺肌病与子宫肌瘤有一定的鉴别诊断价值。

Serum CA125 Assay in Patients with Adenomyosis and Uterine Leiomyoma

Objective To investigate the value of serum CA125 assays in the diagnosis of adenomyosis and.uterine leiomyoma.Method 101 cases of adenomyosis,374 cases of uterine leiomyoma and 32 cases of uterine leiomyoma complicated with adenomyosis were studied.The serum CA125 level was determined by immunoradiometric assay(IRMA).Results The CA125 positive rate(CA125>35 kU/L) of the above three groups was 88.12%,12.30% and 87.50% respectively.The mean CA125 level of the above three groups were 118.37±78.21 kU/L,17.45±14.36 kU/L and 106.49±63.91 kU/L respectively.The mean CA125 level and the positive rate in patients with uterine leiomyoma were significantly lower than those in other two groups( P <0.05).The differences in the mean CA125 level and the positive rate between the patients with adenomyosis and uterine leiomyoma complicated with adenomyosis were not significant( P >0.05).Conclusions Serum CA125 assay is of great assistance to the diagnosis of uterine adenomyosis,and of a certain value to the differential diagnosis between adenomyosis and uterine leiomyoma.