宁水汤治疗慢性肾小球肾炎66例临床观察

目的观察宁水汤治疗慢性肾小球肾炎的临床疗效。方法将102例慢性肾小球肾炎患者随机分为2组。对照组36例予西医常规治疗;治疗组66例在对照组治疗基础上予自拟宁水汤。2组均治疗3个月,观察临床疗效及相关实验室检查指标的改善情况。结果治疗组总有效率97.0%,对照组总有效率77.8%,2组比较差异有统计学意义（P〈0.05）,治疗组疗效优于对照组;2组治疗后血肌酐、血尿素氮、24 h尿蛋白定量均降低,血红蛋白升高,与本组治疗前比较差异均有统计学意义（P〈0.05）;2组治疗后血肌酐、血尿素氮、24 h尿蛋白定量及血红蛋白组间比较差异均有统计学意义（P〈0.05）;2组治疗后尿红细胞计数与治疗前比较差异均有统计学意义（P〈0.05）,治疗组低于对照组,且2组治疗后比较差异有统计学意义（P〈0.01）。结论宁水汤治疗慢性肾小球肾炎有较好的临床疗效,能延缓慢性肾小球肾炎的进程。

Clinical observation of Ningshui decoction on chronic glomerulonephritis

Objective To observe the effect of Ningshui decoction on chronic glomerulonephritis.Methods 102 patients with chronic glomerulonephritis were randomly divided into two groups.Patients in control group（n=36） received routine western medicine therapy.66 cases in treatment group were treated by combination of routine western medicine and Ningshui decoction.The clinical effect and improvement of related indexes of laboratory examinations were compared in two groups after three months of treatment.Results The total effective rate in treatment group（97.0%） was higher than that in control group（77.8%,P0.05）.There was significant difference between before and after treatment on Cr,BUN,24 h urine protein and Hgb in two groups（P0.05）.The levels of Cr,BUN,24 h urine protein and Hgb in treatment group were lower than those in control group after treatment（P0.05）.Conclusion Ningshui decoction has a good effect on chronic glomerulonephritis,and can delay progress of chronic glomerulonephritis.