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| 乳腺癌肿瘤标志物CA15-3和CEA联合检测的临床意义 | |
| 引用本文： | 王建国,王贯宇,吴煜龙,陈志华,赵禹.乳腺癌肿瘤标志物CA15-3和CEA联合检测的临床意义[J].河北职工医学院学报,2011,28(1):35-37. |
| 作者姓名： | 王建国 王贯宇 吴煜龙 陈志华 赵禹 |
| 作者单位： | 1. 河北大学附属医院,河北保定,071000 2. 衡水市公安消防支队后勤处,河北衡水,053000 3. 保定市公安消防支队后勤处,河北保定,071000 4. 河北大学,河北保定,071000 |
| 摘 要： | 目的探讨联合检测血清中CA15-3和CEA水平对乳腺癌的诊断价值。方法用化学发光免疫测定法（CLIA）检测97例乳腺癌患者、74例乳腺增生患者和50例正常女性对照组的血清CA15-3和CEA水平,评价其在乳腺癌中的诊断价值。结果以CA15-3〉30U/mL、CEA〉15ng/mL为判断上限时,其诊断敏感度分别为33%和17.5%,而CA15-3和CEA联合检验测时,其敏感度可达48.5%,具有统计学意义（P〈0.05）。结论联合检测血清CA15-3和CEA水平有助于乳腺癌的诊断。 |
| 关 键 词： | 乳腺癌 CA15-3 CEA 诊断 |
Effects of concentration of CA15-3 and CEA in patient's serum on the diagnosis and prognosis of the breast cancer |
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| WANG Jianguo,WANG Guanyu,WU Yulong,CHEN Zhihua,ZHAO Yu.Effects of concentration of CA15-3 and CEA in patient's serum on the diagnosis and prognosis of the breast cancer[J].Journal of Hebei Medical College for Continuing Education,2011,28(1):35-37. | |
| Authors: | WANG Jianguo WANG Guanyu WU Yulong CHEN Zhihua ZHAO Yu |
| Institution: | WANG Jianguo1,WANG Guanyu2,WU Yulong3,CHEN Zhihua4,ZHAO Yu4(1.Affiliated Hospital of Hebei University,Baoding 071000,China,2.Logistics of office of Public security Fire Control Detachment of Hengshui,Hengshui 053000,3.Logistics of office of Public security Fire Control Detachment of Baoding,4.Hebei University,China) |
| Abstract: | Objective To study the effects of concentration of CA15-3 and CEA in patient’s serum on the diagnosis and prognosis of the breast cancer.Methods The concentration of serum CA15-3 and CEA in 97 patients with breast cancer,74 women with Benign Disease and 50 healthy women were detected by chemiluminescent immunoassay to evaluate the diagnostic and prognosis effects of CA15-3 and CEA on the breast cancer.Result Given CA15-330U/mL,CEA15ng/mL,its positive rate were 33% and 17.5%;but it could advance to 48.5% when allied with CA15-3 and CEA in the examination.Conclusion Examining the concentration of CA15-3 and CEA with allied menthods would be helpful in the diagnosis and prognosis of the breast cancer. |
| Keywords: | CA15-3 CEA |
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