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THE LIVER PEPTIDES AFTER CHRONIC ADMINISTRATION OF ETHANOL IN RATS
Authors:FARBISZEWSKI, R.   GABRYEL, H.
Affiliation:Department of Inorganic and Analytical Chemistry, Medical Academy PI 15–230 Bialystok 8, Poland
Abstract:The liver peptide fractions labelled with 3H-arginine afterchronic administration of ethanol to rats have been analysedby gel filtration chromatography and tlc. Specific 3H-arginineradioactivity in the liver peptide fraction calculated per µgof {alpha}-amino nitrogen was significantly decreased by alcohol. Theamount of peptide spots obtained by tlc in the ethanol-treatedgroup was reduced in comparison with the control group. Thefindings suggest a change in the protein metabolism in hepaticdysfunction in rats receiving ethanol over a prolonged period.
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