放射性核素肝胆显像诊断先天性胆道闭锁的临床价值

目的:回顾性评价99mTc-EHIDA肝胆显像诊断先天性胆道闭锁(BA)的临床价值。方法:应用SPECT仪器对59例临床上持续黄疸的新生儿和婴儿进行99mTc-EHIDA肝胆显像,并经手术病理诊断及随访确诊。结果:最终诊断为BA的34例患儿中,99mTc-EHIDA肝胆显像全部检出;非BA组25例中23例为真阴性,2例为假阳性,灵敏度为100%,特异性92%,准确度96.6%。结论:99mTc-EHIDA肝胆显像是一种无创、安全、有效的检查方法,有助于明确病因,预测治疗效果,对于BA的诊断有较高的临床价值。

Clinical Value Of Radionuclide Hepatobiliary Scintigraphy on Diagnosis of Congential Biliary Atresia

Objective To retrospectively evaluate the diagnostic value of 99 mTc-EHIDA hepatobiliary scintigraphy in congential biliary atresia(BA).Methods Forty-nine infants and neonates(34 infants with BA,the other 25 with non—BA)with consistent jaundice received 99 mTc-EHIDAhepatobiliary scintigraphy with SPECT instrument,the results of all patients were proved by pathology and clinical follow-up results.Results 99 mTc-EHIDA hepatobiliary scintigraphy diagnosed 34 infants and neonates with last diagnosis BA correctly;23 infants and neonates with last diagnosis non-BA correctly,but 2 neonates false-positive in all non-BA 25 patients.The sensitivity,specificity and correct rate of this method were 100%,92% and 96.6%,respectively.Conclusion 99 mTc-EHIDA hepatobiliary scintigraphy is an anoninvasive,safety,valuable examing method.It will help us definite the etilogy,predict the therapeutic efficacy,and have high clinical value in the diagnosis of BA.