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Sub-chronic sulforaphane exposure in CD-1 pregnant mice enhances maternal NADPH quinone oxidoreductase 1 (NQO1) activity and mRNA expression of NQO1, glutathione S-transferase,and glutamate-cysteine ligase: Potential implications for fetal protection against toxicant exposure
Institution:1. Department of Biomedical and Molecular Sciences, Graduate Program in Pharmacology and Toxicology Graduate Program, Queen''s University, Kingston, Ontario, Canada K7L 3N6;2. School of Environmental Studies, Queen''s University, Kingston, Ontario, Canada K7L 3N6;1. Food and Nutritional Sciences Programme, School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong;2. Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong;1. National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Wuhan, Hubei 430070, China;2. MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agricultural University, Wuhan, Hubei 430070, China;3. Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Wuhan, Hubei, China;4. Department of Biosciences, COMSATS Institute of Information Technology, Sahiwal, Pakistan;1. Division of Cardiology, Department of Medicine, Hôpital du Sacré-Coeur de Montréal, Université de Montréal, Monreal, Quebec, Canada;2. Division of Non Invasive Cardiology, Department of Medicine, Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada;3. Division of Cardiac Surgery, Department of Surgery, Hôpital du Sacré-Coeur de Montréal, Université de Montréal, Montréal, Quebec, Canada;1. Department of Obstetrics and Gynecology, Shandong University, Qilu Hospital, No. 104 Culture West Road, Jinan, 250012, Shandong, China;2. Department of Obstetrics and Gynecology, Liaocheng People’s Hospital, No.67 of Dongchang West Road, Liaocheng, 252000, Shandong, China;3. Drug Clinical Trial Institution, Liaocheng People’s Hospital, No.67 of Dongchang West Road, Liaocheng, 252000, Shandong, China
Abstract:
Keywords:Sulforaphane  GST  HO-1  Gclc  NQO1
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