胸腺切除治疗重症肌无力34例体会

1995 - 0 4～ 2 0 0 3- 0 9,采用胸腺切除治疗重症肌无力 34例。年龄 5～ 6 2岁。术后早期死亡 1例 ,死亡率 2 9 4 %。 33例随访 3个月～ 12年。 1年内缓解和改善率 87 9% (2 9/ 33) ,1～ 3年缓解和改善率为88 5 % (2 3/ 33) ,3年以上缓解和改善率为 80 0 % (4 / 5 )。随访结果表明 ,胸腺切除治疗重症肌无力效果满意。延迟拔除气管插管或早期行气管切开术 ,是防治术后重症肌无力危象的有效措施。胸腺肿瘤已浸及包膜或有局限性恶变的患者术后放疗可以减少复发率 ,延长生存时间。

Experience of Treatment on Myasthenia Gravis with Thymectomy

cases of myasthenia gravis were treated with thymectomy from April 1995 to September 2003 with age from 5～62 years old. The 1 case was early death after operation. The mortality was 29.4% after 3 months to 12 years follow-up. The remission rate was 87.9% within 1 year, 88.5% 1～3 years and 80% over 3 years with satisfactory effect. the delayed ex-tubation or early trachetomy might be effective procedure to prevent the MG crisis. The radiotherapy could reduce the relapse rate and prolong the survival for invasive thymoma at capsule and local invasion.