| 人窦房结中突触素增龄性变化的定量研究 |
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| 引用本文： | 宋一璇,姚青松,邓平,梁赏猷,王穗保,汪冠三. 人窦房结中突触素增龄性变化的定量研究[J]. 神经解剖学杂志, 2000, 16(1): 37-39 |
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| 作者姓名： | 宋一璇 姚青松 邓平 梁赏猷 王穗保 汪冠三 |
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| 作者单位： | 1. 广州市刑事科学技术研究所,广州,510030
2. 广州医学院,神经科学研究所,广州,510182 |
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| 基金项目： | 国家自然科学基金资助项目(No．39170396) |
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| 摘 要： | 为了探讨正常人窦房结中突触素增龄性变化的规律 ,用免疫组织化学方法显示窦房结中的突触素 ,并用计算机图像分析技术测量突触素的免疫阳性物面积。结果显示 :窦房结中的突触素阳性物在 1岁以前较少 ,1岁以后显著增多 ,并在 1～ 2 0岁年龄组达到最多 ,其后随年龄增长而减少 ,70岁以后降到最低。提示窦房结中的神经组织在生理状态下存在着增龄性变化
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| 关 键 词： | 窦房结 突触素 增龄性变化 人 |
| 修稿时间： | 1999-04-26 |
QUANTITATIVE STUDIES ON THE AGE-RELATED CHANGES OF SYNAPTOPHYSIN IN HUMAN SINO-ATRIAL NODE |
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| Song Yixuan,Yao Qingsong,Deng Ping,Liang Shangyou,Wang Suibao,Wang Guansan. QUANTITATIVE STUDIES ON THE AGE-RELATED CHANGES OF SYNAPTOPHYSIN IN HUMAN SINO-ATRIAL NODE[J]. Chinese Journal of Neuroanatomy, 2000, 16(1): 37-39 |
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| Authors: | Song Yixuan Yao Qingsong Deng Ping Liang Shangyou Wang Suibao Wang Guansan |
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| Affiliation: | Song Yixuan,Yao Qingsong;(Guangzhou Institute of Criminainalistics, Guangzhou 510030);Deng Ping;(Research Institute of Neuroscience, Guangzhou Medical College, Guangzhou 510182);Liang Shangyou,Wang Suibao,Wang Guansan;(Guangzhou Institute of Criminainalistics, Guangzhou 510030) |
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| Abstract: | To study the regularity of the age related changes of synaptophysin in normal human sino atrial node, the synaptophysin in sino atrial node was stained immunohistochemically, and the positive areas of synaptophysin were measured by computerized image analysis. The results showed that the amount of synaptophysin positivity in the sino atrial node was relatively small before 1 year of age, then increased and reached to maximum in 1～20 years group followed by decrease with aging. After 70 years of age, the amount of synaptophysin positivity was reduced to a minimum. It is indicated that there were age related changes of neural tissue in normal sino atrial node. (Figures 1～4 on plate 6) |
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| Keywords: | sino-atrial node. Synaptophysin age-related change human |
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