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联合紫杉醇化疗晚期恶性肿瘤24例
引用本文:张小华,罗伟炎,罗雄辉,陈育文.联合紫杉醇化疗晚期恶性肿瘤24例[J].赣南医学院学报,2002,22(5):522-523.
作者姓名:张小华  罗伟炎  罗雄辉  陈育文
作者单位:广东兴宁市人民医院肿瘤科,广东,兴宁,514500
基金项目:梅州市医药卫生科研课题基金资助
摘    要:目的:评价联合紫杉醇化疗晚期恶性肿瘤的疗效.方法:观察对象为肺癌10例,乳腺癌8例,卵巢癌5例,鼻咽癌1例.联合化疗方案中紫杉醇135mg/m2,静滴3小时,4周1个疗程,共2~3周期,其它药物为卡铂、吡柔比星等.结果:总有效率71%,不良反应主要为骨髓抑制、脱发、恶心、呕吐.结论:联合紫杉醇化疗肺癌、乳腺癌、卵巢癌等疗效确切,不良反应可以耐受.

关 键 词:紫杉醇  恶性肿瘤
文章编号:1001-5779(2002)05-0522-02
修稿时间:2002年11月13

Combined Chemotherapy of Paclitaxel and Others for 24 Patients with Malignant Tumor
ZHANG Xiao hua,et al.Combined Chemotherapy of Paclitaxel and Others for 24 Patients with Malignant Tumor[J].Journal of Gannan Medical College,2002,22(5):522-523.
Authors:ZHANG Xiao hua  
Abstract:Objective:To evaluate the effcicacy of Pactitaxel on advanced malignant tumor.Methods:To observe 10 cases with lung cancer,8 casese with breast cancer,5 cases with ovarian cancer and 1 case with nasopharyngeal carcinoma.24 patients were treated by combination chemotherapy of pactitaxel 135mg/m 2,combined with carboplatin or pirarubin was given intravenously for three hours.Each vegimen included 2 to 3 cycle and it was repeated every four weeks.Result:A total response rate for 24 patients was 71%.The major side effects wree tolerable antitumor agent in treatment of lung cancer,breast cancer or ovarian cancer.
Keywords:Paclitaxel  mailgnant tumor
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