| HBeAg阳性慢性乙肝患者红细胞天然免疫粘附功能的变化及意义 |
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| 引用本文： | 罗丽莎,张继万,周建丽,何鹏飞,隆莉,王海滨.HBeAg阳性慢性乙肝患者红细胞天然免疫粘附功能的变化及意义[J].中国卫生检验杂志,2011(8). |
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| 作者姓名： | 罗丽莎 张继万 周建丽 何鹏飞 隆莉 王海滨 |
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| 作者单位： | 武警四川总队医院;解放军302医院临检中心; |
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| 摘 要： | 目的:研究HBeAg阳性慢性乙肝患者红细胞天然免疫粘附功能(red cell nature immune adhesion function,RNIAF)的变化,探讨其临床意义。方法:选择血清HBV DNA大于106 IU/ml的60例肝功能正常、32例初次出现肝功异常及26例反复肝功异常的HBeAg阳性慢性乙肝患者作为研究对象,采用红细胞天然免疫粘附肿瘤细胞功能实验,对118例研究对象及30例正常人的RNIAF进行测定。结果:肝功能正常的HBeAg阳性慢性乙肝患者RNIAF与正常人群比较,无显著差异(P>0.05)。初次出现肝功异常的HBeAg阳性慢性乙肝患者RNIAF显著高于肝功正常的HBeAg阳性患者及正常人群(P<0.01);反复出现肝功异常的HBeAg阳性慢性乙肝患者的RNIAF则显著低于肝功正常的患者及正常人群(P<0.01)。持续肝功异常的HBeAg阳性慢性乙肝患者的RNIAF随着病程延长而逐渐下降,肝功能恢复后其RNIAF有所回升。结论:HBeAg阳性慢性乙肝患者RNIAF的变化与其疾病的不同时期及病情的严重程度密切相关,可作为判断该类患者病情变化的重要指标。
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| 关 键 词： | HBeAg阳性 慢性乙肝 红细胞 免疫粘附 |
Changes and significance of red cell nature immune adhesion function in patients with e antigen positive of chronic hepatitis B |
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| LUO Li-sha,ZHANG Ji-wan,ZHOU Jian-li,HE Peng-fei,LONG Li,WANG Hai-bin.Changes and significance of red cell nature immune adhesion function in patients with e antigen positive of chronic hepatitis B[J].Chinses Journal of Health Laboratory Technology,2011(8). |
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| Authors: | LUO Li-sha ZHANG Ji-wan ZHOU Jian-li HE Peng-fei LONG Li WANG Hai-bin |
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| Institution: | LUO Li-sha1,ZHANG Ji-wan1,ZHOU Jian-li1,HE Peng-fei1,LONG Li1,WANG Hai-bin2(1.Si Chuan Provincial Corps Hospital,Chinese People's Armed Police Forces,Leshan 614000,China,2.Clinical Inspection Center of 302 Military Hospital of China,Beijing 100039,China) |
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| Abstract: | Objective:To study the changes and significance of red cell nature immune adhesion function(RNIAF) in patients with e antigen positive of chronic hepatitis B.Methods:The assay of red cell nature immune-adhering tumor cell was performed in 30 healthy individuals and 118 patients of e antigen positive with HBV DNA more than 106 IU/ml in serum.In those patients,60 cases were with normal hepatic function,32 cases had initially abnormal hepatic function and 26 patients repeatedly abnormal hepatic function.Result... |
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| Keywords: | E antigen positive Chronic hepatitis B Red blood cells Immune adhesion |
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