| 代谢综合征患者血清脂蛋白脂酶含量变化的临床对照研究 |
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| 引用本文： | 徐先静,王丽霞,黄改荣,段明勤,曹选超. 代谢综合征患者血清脂蛋白脂酶含量变化的临床对照研究[J]. 中国卫生检验杂志, 2011, 0(8) |
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| 作者姓名： | 徐先静 王丽霞 黄改荣 段明勤 曹选超 |
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| 作者单位： | 河南省人民医院干部病房心内科; |
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| 摘 要： | 目的:了解代谢综合征(MS)患者的代谢紊乱特点,探讨血清脂蛋白酯酶(LPL)含量与MS的内在联系。方法:通过问卷调查、人体测量及生化检查获得腹围(WC)、收缩压(SBP)、舒张压(DBP)、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、空腹胰岛素(INS)、胰岛素敏感指数(ISI)相关数据,纳入MS组24例和健康对照组24例。进行血清LPL(双抗体夹心ELISA法)和游离脂肪酸(FFA)含量的测定(比色法)。结果:(1)病例组WC、SBP、DBP、TGI、NS和FFA显著高于对照组(P<0.01);HDL-CI、SI、血清LPL含量显著低于对照组(血清LPL含量:43.84±4.43ng/mL vs 50.37±4.41ng/mL,P<0.05),而TC、LDL-C和FPG两组之间差别没有统计学意义(P>0.05);(2)血清LPL含量与WC(r=-0.640)、SBP(r=-0.590)、DBP(r=-0.432)、TG(r=-0.784)和FFA(r=-0.720)呈显著负相关(P<0.01);与ISI(r=0.533)、HDL-C(r=0.463...
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| 关 键 词： | 代谢综合征 肥胖 胰岛素抵抗 脂蛋白脂酶 游离脂肪酸 |
Case control study of serum lipoprotein lipase disturbances in patients with metabolic syndrome |
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| XU Xian-jing,WANG Li-xia,HUANG Gai-rong,DUAN Ming-qin,CAO Xuan-chao. Case control study of serum lipoprotein lipase disturbances in patients with metabolic syndrome[J]. Chinses Journal of Health Laboratory Technology, 2011, 0(8) |
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| Authors: | XU Xian-jing WANG Li-xia HUANG Gai-rong DUAN Ming-qin CAO Xuan-chao |
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| Affiliation: | XU Xian-jing,WANG Li-xia,HUANG Gai-rong,DUAN Ming-qin,CAO Xuan-chao(Department of Cardiology in Cadre Wards,Henan Provincial People's Hospital,Zhengzhou,450003,China) |
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| Abstract: | Objective:Discussing the features of metabolic disturbances in patients with metabolic syndrome,investigating the internal relationship between the LPL mass in serum and metabolic syndrome.Methods:The data of WC,SBP,TG,TC,LDL-C,HDL-C,INS and ISI were obtained with questionnaire,physical measurement and biochemical examination.Then 24 patients with metabolic syndrome formed the experimental group and the other 24 normal individuals were used as the control group.Then,free fatty acid and serum LPL mass were m... |
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| Keywords: | Metabolic Syndrome Obesity Insulin Resistance Lipoprotein Lipase Free Fatty Acids |
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