Protection against increased intestinal permeability and bacterial translocation induced by intestinal obstruction in mice treated with viable and heat-killed <Emphasis Type="Italic">Saccharomyces boulardii</Emphasis> |
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| Authors: | Simone V Generoso Mirelle L Viana Rosana G Santos Rosa M E Arantes Flaviano S Martins Jacques R Nicoli José A N Machado Maria Isabel T D Correia Valbert N Cardoso |
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| Institution: | Departamento de Análises Clinicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, C.P. 486, Belo Horizonte, MG, 30161-970, Brazil. simonenut@yahoo.com.br |
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| Abstract: | Background There are substantial evidences suggesting that probiotics can protect the gastrointestinal tract against inflammatory or
infectious episodes. The effects of oral treatment with viable or heat-killed cells of Saccharomyces boulardii (Sb) on bacterial translocation, intestinal permeability, histological aspect of the ileum, and some immunological parameters
were evaluated in a murine intestinal obstruction (IO) model. |
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