18例胃白念珠菌病并发胃癌的内镜病理分析

胃癌的病因至今尚未完全明了，真菌的致胃癌作用近年来受到重视。本文对病理确诊的１８例胃白念珠菌病并发胃癌作了内镜和病理分析。结果明显：白念珠菌常见于溃疡型（６１．１％）和浸润型（２７．８％）的胃癌组织中，组织分型则以分化性腺癌（３８．９％）和粘液腺癌（２７．８％）为主。大部分白念珠菌位于组织的粘膜层（８８．９％）。白念珠菌的致胃癌作用可能与其产生的Ⅱ级胺、黄曲霉毒素Ｇ１、Ｂ２等有关。白念珠菌在胃癌的发生、发展上可能起一定的作用。我们从活检粘膜病理方面作了分析。

THE ENDOSCOPIC AND PATHOLOGICAL ANALYSES OF EIGHTEEN CASES OF GASTRIC CANDIDIASIS WITH GASTRIC CANCER

The etiology of gastric cancer is still unknown.Recently,carcinogensis of fung was paid attention.This paper analyses eighteen cases of gastric candidiasis with gastric cancer which were diagnosed with endoscopic and pathological examinations. The results showed that candida albicans were often detected in ulcerous and invasive gastric cancer(61.1 % and 27. 8%,respectively) . Histologically, well-differentiated and mucinous adenocarcinomas account for 38. 9% and 27. 8%, respectively. The most candida albicans located in the layer of mucosa ( 88. 9%). Carcinogensis of candida albicans is likely to be associated with second-class amines and aflatoxin Gl, B2. It may play a role in the pathogenesis and development of gastric cancer.