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Elevated circulating levels of osteopontin are associated with metastasis in advanced non-small cell lung cancer |
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| Authors: | Yong Liang Hui Li Bin Hu Xing Chen Jin-bai Miao Tong Li Bin You Qi-rui Chen Yi-li Fu Yang Wang Sheng-cai Hou |
| Institution: | Yong Liang,Hui Li*,Bin Hu,Xing Chen,Jin-bai Miao,Tong Li,Bin You,Qi-rui Chen,Yi-li Fu,Yang Wang,Sheng-cai Hou Department of Thoracic Surgery and Central Laboratory,Beijing Key Laboratory of Respiratory and Circulation,Beijing Chao-Yang Hospital,Beijing Institute of Respiratory Medicine,Capital Medical University,Beijing 100020,China |
| Abstract: | Objective:To investigate the relationship between postoperative metastasis and circulating levels of osteopontin in non-small cell lung cancer(NSCLC).Methods:The expression of osteopontin mRNA were detected with RT-PCR technique.The circulating levels of osteopontin were measured through ELASA in 46 NSCLC cases that had not been received any anti-cancer treatment at the time of sampling.The tissues from fifteen patients with benign pulmonary diseases were studied as control group.Results:The overall median ... |
| Keywords: | Osteopontin Non-small cell lung cancer Metastasis Prognosis |
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