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冬虫夏草对垂体后叶素所致大鼠缺血心肌的保护作用
引用本文:李雪芹,刘建云. 冬虫夏草对垂体后叶素所致大鼠缺血心肌的保护作用[J]. 河北医药, 2004, 26(12): 934-935
作者姓名:李雪芹  刘建云
作者单位:332000,江西省九江市,九江学院医学院药理教研室;九江学院医学院基础学实验中心
摘    要:目的 观察冬虫夏草对急性缺血心肌的保护作用。方法 采用垂体后叶素所致大鼠急性缺血模型观察药物的作用。结果 冬虫夏草和维拉帕米能明显缓解垂体后叶素所引起的心电图T波变化 (P <0 .0 1) ,垂体后叶素使 10 0 %的动物发生心律失常 ,而在冬虫夏草组及维拉帕米组 ,心律失常的发生律分别为 18% (P <0 .0 1)和 12 % (P <0 .0 1)。结论 冬虫夏草对垂体后叶素所致急性缺血心肌具有保护作用。

关 键 词:冬虫夏草  垂体后叶素  缺血心肌

Protective effects of Crodyceps on myocardial ischemia induced by pituitrin in rats
Li Xueqin,LIU Jianyun. Protective effects of Crodyceps on myocardial ischemia induced by pituitrin in rats[J]. Hebei Medical Journal, 2004, 26(12): 934-935
Authors:Li Xueqin  LIU Jianyun
Affiliation:LI Xueqin,LIU Jianyun.Department of Pharmacology,Jiujiang Medical College,Jiujiang 332000
Abstract:Objective To investigate the protective effects of Crodyceps on acute myocardial ischemia induced by pituitrin in rats.Methods The experiment was performed in the model of acute myocardial ischemia induced by pituitrin in SD rats.Results Crodyceps and verapamil significantly inhibited the changes of T wave in ECG caused by pituitrin at most of the period (P<0.01).Crodyceps could induce arrhythmia in 100% animals,however,in Crodyceps group and verapamil group,the incidences of arrhythmia were 10% (P<0.01) and 12% (P<0.01) respectively.Conclusion Crodyceps has the protective effects on acute myocardial ischemia induced by pituitrin in rats.
Keywords:Crodyceps  pituitrin  myocardial ischemia
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