| 移植胰岛功能保护的研究进展 |
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| 引用本文： | 武晓泓,张梅,刘超. 移植胰岛功能保护的研究进展[J]. 国际内分泌代谢杂志, 2006, 26(6): 394-396,399 |
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| 作者姓名： | 武晓泓 张梅 刘超 |
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| 作者单位： | 210029,南京医科大学第一附属医院内分泌科 |
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| 摘 要： | 移植胰岛的坏死和凋亡严重影响胰岛移植的效果。近年来通过改善供体胰腺组织的保存、胰岛分离和纯化方法,抑制非特异性炎症反应,减轻经血液介导的瞬时炎症反应,诱导免疫耐受和基因修饰胰岛移植等措施,移植胰岛的功能保护研究取得了一定进展。
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| 关 键 词： | 糖尿病 胰岛移植 移植物 |
| 收稿时间： | 2005-11-29 |
| 修稿时间： | 2005-11-29 |
Advances in the protection of islet grafts function |
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| WU Xiao-hong,ZHANG Mei,LIU Chao. Advances in the protection of islet grafts function[J]. International JOurnal of Endocrinology and Metabolism, 2006, 26(6): 394-396,399 |
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| Authors: | WU Xiao-hong ZHANG Mei LIU Chao |
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| Affiliation: | Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China |
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| Abstract: | The outcome of islet transplantation is mainly impacted by the necrosis and apoptosis of islet grafts. Recently, studies on the protection of islet grafts function have made a certain progress through the improvement of donor pancreas procurement and preservation, islet isolation and purification, inhibition of non-specific and instant blood-mediated inflammatory reaction, induction of immune tolerance and gene-modified islet transplantation. |
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| Keywords: | Diabetes Islet transplantation Graft |
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