乌鲁木齐地区0～14岁儿童脂溶性维生素营养水平现状研究

目的研究乌鲁木齐地区0~14岁儿童脂溶性维生素A、D、E、K营养水平。方法选取2018年11月至2019年3月该院体检儿童264例,分为婴幼儿组(0~<3岁)104例,学龄前组(3~<6岁)75例,学龄组(6~<14岁)85例,利用液相色谱串联质谱法检测血清中维生素A、D、E及K水平。结果维生素D在男童中水平为(22.13±13.79)ng/mL,在女童中水平为(18.85±12.06)ng/mL,男童明显高于女童,差异有统计学意义(P<0.05)。维生素A、E、K在男、女童之间水平比较,差异无统计学意义(P>0.05)。维生素A水平为(0.30±0.08)mg/L,缺乏率为11.7%,婴幼儿组缺乏率最高(17.3%)。维生素D水平为(20.80±13.19)ng/mL,缺乏率、不足率和为60.3%,随着年龄的增加,缺乏率有所增加。维生素E水平为(10.22±2.20)mg/L,不足率为4.9%,整体处于正常水平。维生素K水平为0.36(0.19~0.69)ng/mL,缺乏率为13.3%,婴幼儿组及学龄前组儿童中缺乏较多,缺乏率分别为11.5%、18.7%。结论乌鲁木齐地区儿童脂溶性维生素存在整体缺乏的情况,在医生的指导下正确、及时地检测和合理地补充脂溶性维生素,有助于儿童的健康成长。

Study on the nutritional status of fat-soluble vitamins among children aged 0-14 years old in Urumqi

Objective To study the fat-soluble vitamin A,D,E,and K nutritional levels of children aged 0 to 14 years old in Urumqi.Methods From November 2018 to March 2019,264 children undergoing physical examination in the hospital were selected,which were divided into 104 cases of infants(0-<3 years old),75 cases of preschool children(3-<6 years old),and 85 cases of school age children(6-<14 years old).The levels of vitamin A,D,E and K in serum were detected by liquid chromatography-tandem mass spectrometry.Results The level of vitamin D was(22.13±13.79)ng/mL in boys and(18.85±12.06)ng/mL in girls.Boys were significantly higher than girls(P<0.05).There was no significant difference in vitamin A,E,K levels between boys and girls(P>0.05).Vitamin A level was(0.30±0.08)mg/L,the deficiency rate was 11.7%,and the deficiency rate was highest in infants and young children(17.3%).The vitamin D level was(20.80±13.19)ng/mL,and the deficiency rate and deficiency rate were 60.3%.As the age increased,the deficiency rate increased.Vitamin E level was(10.22±2.20)mg/L,the deficiency rate was 4.9%,and the overall level was normal.Vitamin K levels were 0.36(0.19-0.69)ng/mL,with a deficiency rate of 13.3%.Children in the infant group and preschool group were more deficient,with deficiency rates of 11.5% and 18.7%,respectively.Conclusion The overall lack of fat-soluble vitamins in children in Urumqi region.The correct and timely detection and reasonable supplementation of fat-soluble vitamins under the guidance of doctors will help children grow up healthy.