老年慢性失眠相关认知障碍的危险因素分析

目的探讨老年慢性失眠相关认知障碍的危险因素。方法回顾性筛选老年慢性失眠患者107例,根据蒙特利尔认知评估量表(Mo CA)评分将患者分为认知障碍组与非认知障碍组。比较两组患者一般临床资料、失眠严重程度指数(ISI)、匹兹堡睡眠质量量表(PSQI)评分、汉密顿抑郁量表(HAMD)、焦虑量表(HAMA)评分,睡眠观念态度量表(DBAS)评分等。采用多因素logistic回归分析探讨老年慢性失眠相关认知障碍的独立危险因素。结果多因素logistic回归分析显示,主观睡眠障碍(OR=16. 064,P=0. 003)、睡眠潜伏期(OR=10. 567,P=0. 032)、习惯性睡眠效率(OR=21. 697,P=0. 006)、睡眠紊乱(OR=24. 754,P=0. 008)是老年慢性失眠患者相关认知障碍的独立危险因素。结论主观睡眠质量差、睡眠潜伏期长、习惯性睡眠效率低、睡眠紊乱严重是老年慢性失眠患者罹患认知障碍的独立危险因素。

An analysis of risk factors for chronic insomnia-related cognitive impairment in the elderly

Objective To investigate the risk factors for chronic insomnia-related cognitive impairment in the elderly.Methods A total of 107 elderly patients with chronic insomnia were retrospectively screened and divided into cognitive impairment group and non-cognitive impairment group according to the Montreal Cognitive Assessment score. The general clinical data, Insomnia Severity Index, Pittsburgh Sleep Quality Index, Hamilton Depression Scale score, Hamilton Anxiety Scale score, and Dysfunctional Beliefs and Attitudes about Sleep Scale score were compared between the two groups. A multivariate logistic regression analysis was used to explore the independent risk factors for chronic insomnia-related cognitive impairment in the elderly.Results The multivariate logistic regression analysis showed that subjective sleep disturbance (odds ratioOR]=16.064, P=0.003), sleep latency (OR=10.567, P=0.032), habitual sleep efficiency (OR=21.697, P=0.006), and sleep disorder (OR=24.754, P=0.008) were independent risk factors for chronic insomnia-related cognitive impairment in the elderly.Conclusions Poor subjective sleep quality, long sleep latency, low habitual sleep efficiency, and severe sleep disorder are independent risk factors for cognitive impairment in elderly patients with chronic insomnia.