益气化瘀汤合沙参麦冬汤辅助化疗对气阴两虚型肺癌患者肿瘤控制率及机体状况的影响

目的 探讨益气化瘀汤合沙参麦冬汤辅助GP方案化疗(吉西他滨+顺铂)对气阴两虚型肺癌患者肿瘤控制率及机体状况的影响.方法 选取2017年11月至2019年2月我院收治的肺癌患者102例,按照随机数字表法分为对照组(51例)与试验组(51例).对照组采取GP化疗方案,试验组在对照组基础上加用益气化瘀汤合沙参麦冬汤.统计两组...

Effects of the auxiliary chemotherapy with Yiqi Huayu Decoction and Shashen Maidong Decoction on tumor control rate and body condition in patients with lung cancer with deficiency of Qi and Yin

Objective To investigate the effect of auxiliary Gemcitabine+Cisplatin chemotherapy with Yiqi Huayu Decoction and Shashen Maidong Decoction on tumor control rate and body condition in patients with lung cancer with Qi and Yin deficiency.Methods From November 2017 to February 2019,102 patients with lung cancer were treated in our hospital and they were divided into control group(n=51)and experimental group(n=51)according to the random number table method.The control group was treated with GP chemotherapy,and the experimental group was supplemented with Yiqi Huayu Decoction and Shashen Maidong Decoction on the basis of the treatment for control group.The tumor control rate,TCM syndrome scores before and after treatment,body condition,immune function,and toxic side effects were recorded.Results(1)Tumor control rate:the tumor control rate of experimental group(86.27%)was slightly higher than that of control group(78.43%),but there was no significant difference(P>0.05).(2)TCM syndrome score:after treatment,the spontaneous sweating,dry mouth,dry mouth,fatigue,and cough scores decreased in the two groups(P<0.05),and the experimental group was lower than the control group(P<0.05).(3)The body condition:the KPS stability rate of experimental group(80.39%)was higher than that of control group(62.75%)(P<0.05).(4)Immune function:CD3+,CD4+,CD4+/CD8+in experimental group were higher than those in control group after treatment(P<0.05).(5)Toxic side effects:no gradeⅣside effects occurred in the two groups,and the incidence of hemoglobin reduction,liver and kidney function damage,vomiting and nausea,and leukopenia was lower in experimental group than in control group(P<0.05).Conclusion The auxiliary treatment with Yiqi Huayu Decoction and Shashen Maidong Decoction in patients with lung cancer with deficiency of Qi and Yin can effectively regulate the patient′s body condition and immune function,improve clinical symptoms,and have high tumor control rate and can reduce toxic side effects.