| 天然药物防治阿尔茨海默病的研究进展 |
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| 引用本文： | 刘涛,胡海涛.天然药物防治阿尔茨海默病的研究进展[J].医学综述,2012,18(10):1499-1501. |
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| 作者姓名： | 刘涛 胡海涛 |
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| 作者单位： | 西安体育学院运动人体科学系;西安交通大学医学院解剖与组织胚胎学教研室 |
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| 基金项目： | 陕西省教育厅基础科研项目(11JK0625) |
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| 摘 要： | 阿尔茨海默病(AD)是一种以神经元丢失和痴呆为主要症状的神经退行性疾病,它的病理症状主要是细胞外β淀粉样蛋白沉积形成的老年斑和细胞内神经纤维缠结形成的tau蛋白。尽管AD治疗方面的研究较多,但真正能够治愈AD的药物还未发现。一些神经保护性药物正尝试被用于保护正常细胞免受应激干扰或减少病理条件下神经元的丢失。天然药物作为一种神经保护性药物受到越来越多的关注,现就近年来阿尔茨海默病治疗的天然药物的研究进展予以综述。
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| 关 键 词： | 阿尔茨海默病 天然药物 药理效应 |
Research Progress of the Treatment to Alzheimer Disease with Natural Drugs |
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| LIU Tao,HU Hai-tao.Research Progress of the Treatment to Alzheimer Disease with Natural Drugs[J].Medical Recapitulate,2012,18(10):1499-1501. |
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| Authors: | LIU Tao HU Hai-tao |
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| Institution: | 1.Department of Sports Human Body Science,Xi′an Physical Education University,Xi′an 710068,China;2.Department of Human Anatomy and Histology Embryology,Medical School of Xi′an Jiaotong University,Xi′an 710061,China) |
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| Abstract: | Alzheimer disease(AD)is a neurodegenerative disease characterized by the progressive neuron loss and dementia associated with deposits of β-amyloid in senile plaques and accumulation of abnormal tau filaments in neurofibrillary tangles.Although many studies have been directed to AD treatment,there is still no promising intervention for curing the disease.Neuroprotection is the attempt to preserve normal cellular interaction in the brain and minimize loss of neuronal functions in pathological conditions.Currently,much attention has been focused on the potential of using natural herbs as neuroprotective agent.Here is to make a review on the progress in natural drugs for treating AD. |
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| Keywords: | Alzheimer disease Natural drugs Pharmacological effect |
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