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金钱草颗粒剂的药效学研究
引用本文:沈德凤,焦艳,沈洪宽,宋岳. 金钱草颗粒剂的药效学研究[J]. 黑龙江医药科学, 2009, 32(3)
作者姓名:沈德凤  焦艳  沈洪宽  宋岳
作者单位:佳木斯大学化学与药学院,黑龙江,佳木斯,154007;佳木斯市药品检验所,黑龙江,佳木斯,154007
摘    要:目的:探讨金钱草颗粒剂的药理作用.方法:建立动物实验模型,抗炎实验:通过小鼠耳廓二甲苯致炎,以左右耳片重量差为肿胀程度,计算各组肿胀度;利胆实验:采用胆管引流法测定金钱草颗粒对大鼠胆汁流量变化的影响.结果:金钱草颗粒可抑制由二甲苯所致小鼠耳廓肿胀,且各剂量组与空白对照组比较均有显著性差异(P<0.01);能明显增加胆汁分泌量,且中剂量组效果最佳,3h累积胆汁量为(1.68±0.02)mL,与空白对照组比有显著性差异(P<0.05,P<0.01).结论:金钱草颗粒有显著的消炎利胆作用,对胆囊炎有很好的治疗作用.

关 键 词:金钱草颗粒剂  抗炎  利胆  胆囊炎

Pharmacodynamics of Christina Loosestrife Herb granules
SHEN De-feng,JIAO Yan,SHEN Hong-kuan,SONG Yue. Pharmacodynamics of Christina Loosestrife Herb granules[J]. Heilongjiang Medicine and Pharmacy, 2009, 32(3)
Authors:SHEN De-feng  JIAO Yan  SHEN Hong-kuan  SONG Yue
Affiliation:1.College of Chemistry and Pharmacy of Jiamusi University;Jiamusi 154007;China;2.Jiamusi Institute for Drug Control;China
Abstract:Objective: To study the main pharmacological action of Christina Loosestrife Herb granules.Methods:To establish animal experimental model,Anti-inflammatory experiment was carried out as follows:proinflammatory action was caused by the mouse auricle xylene,with the left right ear piece weight difference as the swelling degree,the swelling of each group was calculated.Cholagogue experiments was carried out as follows:the bile duct drainage was used to determine the effect of Christina Loosestrife Herb granule...
Keywords:Christina Loosestrife Herb granules  Anti-inflammatory  Cholagogue  Cholecystitis  
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