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肠缺血/再灌注引起肝功能损伤的研究进展
引用本文:鲁智英,吴学东. 肠缺血/再灌注引起肝功能损伤的研究进展[J]. 医学综述, 2012, 0(24): 4128-4130
作者姓名:鲁智英  吴学东
作者单位:大理学院附属医院;大理学院临床医学研究中心小儿外科
基金项目:云南省自然科学基金(2009ZC121M)
摘    要:肠缺血/再灌注通过一系列发病机制可以导致严重的肝肠组织损伤。目前国内外关于引起肝损伤发病机制的前瞻性研究仍不多,因此明确肝损伤的发病机制对临床治疗并预防肠缺血/再灌注引起肝功能损伤有长远的意义。近年来,肠缺血/再灌注的发病机制主要是从肠道屏障损伤、肠缺血以及再灌注等方面进行研究。

关 键 词:肠缺血/再灌注  肝功能损伤  发病机制

Research Progress of Hepatic Injury Caused by Intestinal Ischemia/Reperfusion
LU Zhi-ying,WU Xue-dong. Research Progress of Hepatic Injury Caused by Intestinal Ischemia/Reperfusion[J]. Medical Recapitulate, 2012, 0(24): 4128-4130
Authors:LU Zhi-ying  WU Xue-dong
Affiliation:.(Department of Pediatric Surgery,Affiliated Hospital and Clinical Medical Research Center of Dali University,Dali 671000,China)
Abstract:Intestinal ischemia/reperfusion(II/R)may cause serious liver and intestinal injury through a series of pathogenesis.Currently there are only few prospective studies of the pathogenesis of liver injury caused by II/R at home and abroad.Therefore,identifying the hepatic injury pathogenesis plays a significant role in long-termfor the clinical treatment and prevention.In recent years,the study of II/R pathogenesis is mostly from the aspects of intestinal barrier damage,intestinal ischemia,and perfusion.
Keywords:Intestinal ischemia-reperfusion  Hepatic injury  Pathogenesis
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