| 白细胞介素-18与2型糖尿病及其微血管病变的相关性研究 |
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| 引用本文： | 程宁,刘素筠,张姬欣,王静,甄璐,程瑞. 白细胞介素-18与2型糖尿病及其微血管病变的相关性研究[J]. 中国医疗前沿, 2012, 0(20): 10-11,82 |
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| 作者姓名： | 程宁 刘素筠 张姬欣 王静 甄璐 程瑞 |
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| 作者单位： | 山西医科大学第二医院 |
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| 摘 要： | 白细胞介素18（IL-18）作为一种前炎症细胞因子,参与了2型糖尿病及其微血管病变的发生、发展。IL-18在胰岛素抵抗及糖尿病病程的发展,可能起到中心介质的作用。IL-18水平变化不但对2型糖尿病及其微血管并发症的预后和临床治疗的评估有一定的价值,也为防治糖尿病及其并发症提供了新的研究方向。现就IL-18与2型糖尿病及其微血管病变的相关性做一综述。
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| 关 键 词： | 白细胞介素18 2型糖尿病 糖尿病微血管病变 |
Progress in Relationship of IL-18 to Type 2 Diabetes and Diabetes capillary pathological changes |
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| Affiliation: | CHENG Ning,IU Su-jun,ZHANG Ji-xin,et al.The Second Hospital of Shanxi Medical University,Taiyuan 030001,China |
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| Abstract: | Interleukin 18（IL-18） as a proinflammatory cytokine involved in the occurrence and development of type 2 diabetes and microvascular disease. IL-18 in the course of the development of insulin resistance and diabetes may play the role of media center. IL-18 levels not only have a certain value on the assessment of prognosis and clinical treatment of type 2 diabetes and microvascular disease complications and provides a new research direction for the prevention and treatment of diabetes and its complications. The following review about progress in relationship of IL-18 to type 2 diabetes and diabetes capillary pathological changes. |
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| Keywords: | Interleukin-18 Type 2 diabetes Diabetes capillary pathological changes |
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