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冠心病心衰患者血清C反应蛋白的变化及氟伐他汀的影响
引用本文:刘维琴,刘洪梅. 冠心病心衰患者血清C反应蛋白的变化及氟伐他汀的影响[J]. 重庆医科大学学报, 2005, 30(6): 915-916
作者姓名:刘维琴  刘洪梅
作者单位:贵阳中医学院附属第二医院心内科,贵阳,55003;贵阳中医学院附属第二医院心内科,贵阳,55003
摘    要:目的:观察慢性心衰患者血清C-反应蛋白(CRP)的变化及氟伐他汀的影响.方法:将慢性心衰患者78例随机分为治疗组与对照组,两组均按慢性心力衰竭治疗指南给予常规治疗,治疗组另外服用氟伐他汀,两组治疗前后检查总胆固醇(TC)、C-反应蛋白、左室射血分数(LVEF).结果:8周后,治疗组TC、CRP与对照组比较均有不同程度的降低,LVEF则有明显提高(均P<0.05).结论:CRP可预测心血管疾病的危险,可作为预测心衰者预后的一个观察指标;氟伐他汀可降低CRP水平,改善心衰患者的预后.

关 键 词:慢性心衰  C反应蛋白  氟伐他汀
文章编号:0253-3626(2005)06-0915-02
收稿时间:2005-05-08
修稿时间:2005-05-08

The changement of serum CRP and the effect of fluvastatin on CRP in the patients with heart failure of CHD
LIU Weiqing. The changement of serum CRP and the effect of fluvastatin on CRP in the patients with heart failure of CHD[J]. Journal of Chongqing Medical University, 2005, 30(6): 915-916
Authors:LIU Weiqing
Affiliation:LIU Weiqing Department of Cardiology,the Second Affiliated Hospital of Guiyang TCM College)
Abstract:Objective; To observe the changement of serum c - reactive protein (CRP) and the effect of fluvastatin on CRP in the patients with heart failure of coronary heart diease (CHD). Methods ; 78 patients with CHFwere randomly divided into treated group and contol group , which were given usual treatment according to the guide of CHF treatment. Meanwhile, fluvastatin was added to the treated group . Two groups need to detected the TC , CRP and LEVF before and after treatment . Results : After 8 weeks , compared to the control group , the TC , CRP of the treated group decreased in varying degredd , but the LEVF increased obviously . Conclusion ; CRP can forecast dangerous of heart disease . It can be used as a index to prognose the patient with CHF . Fluvastatin can decrease the CRP and improve the prognosis for patient with CHF .
Keywords:Chronic heart failure    C - reactive protein    Fluvastatin
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