早期预测难治性癫痫的因素及临床对照分析

目的研究和分析难治性癫痫早期预测因素，为临床上治疗提供理论上的依据。方法选择2009年11月2011年11月门诊患者200例，将其按病情分为两组，即实验组（120例）与对照组（80例）。观察患者一般资料，发作类型，家族史，疾病史，脑部损伤，精神状态和治疗效果。研究癫痫容易发展成难治性癫痫预测因素。结果实验组患者早期就有智能障碍（P〈0．01）、治疗结束后脑电图检测显示仍然存在癫痫波样异常（P〈0．01）、初次来院治疗前病情发作在10次以上（P〈0．01）。结论治疗前癫痫发作次数多、伴有智能障碍、治疗结束后脑电图仍然存在异常、初次治疗效果较差的癫痫患者容易发展为难治性癫痫患者。

The Factors of Early Predictors of Intractable Epilepsy and Its Clinical Contrast Analysis

Objective To study and analyze intractable epilepsy early predictive factors and provide a theoretical basis for clinical treatment. Methods A total of 200 eases of outpatient from November 2009 to November 2011 were divided into two groups according to the disease, that is, the experimental group （120 eases） and control group （80 eases）. Observe patients＇ general information, seizure type, family history, disease history, brain damage, mental state and treatment effect. To research forecast factors of intractable epilepsy. Results The early experimental group patients had mental retardation （ P 〈 0.01 ）, after the end of treatment EEG detection still exist abnormal the epileptic wave-like shape （ P 〈 0.01） first came to the hospital for treatment before the onset of the disease in more than 10 times （P 〈 0.01 ）. Conclusion Patients with epilepsy happened frequently before treatment, with learning disability, electroencephalogram is still abnormal after the treatment and initial treatment effect is poorer are easily become to intractable epilepsy patients.