支气管扩张症患者伴发过敏症的临床研究

目的]探讨变态反应在支气管扩张症中的作用,明确支气管扩张症患者伴发过敏症的状况.方法]对193例支气管扩张症患者进行过敏原皮肤点刺试验(SPT)和伴发的呼吸系统疾病进行对比研究.结果]支气管扩张症患者过敏原SPT阳性率为45.1%,主要过敏原尘螨、蟑螂、狗毛、真菌、艾蒿和虾,分别占SPT阳性患者的比例为91.9%...

Clinical Study of Bronchiectasis Accompanying with Allergic Disease

Objective] To explore the role of allergic reaction in bronchiectasis in order to understand the status of bronchiectasis patients accompanying with allergic disease. Methods] The allergen skin prick test （SPT） and concomitant other diseases of respiratory system in 193 bronchiectasis patients were comparatively studied. Results]The positive rate of allergen SPT in bronchiectasis patients was 45.1%. The main allergens were dust mite, cockroach, dog dander, fungi, wormwood and shrimp, which accounted for 91.9%, 34.5%, 26.4%, 16.1%, 14.9% and 14.9%, respectively. Patients with allergy of single mite, two mites and three mites accounted for 8.8%, 30% and 61.2%, respectively. Among 193 bronchiectasis patients, the patients complicated with bronchial asthma, rhinitis and bronchiectasis alone accounted for 39. 4%, 45. 6% and 35.8%, respectively. And 11 patients were complicated with other lung diseases. There was no significant difference in the positive rate of SPT between male and female patients in all groups. The positive rate of SPT in the group of bronchiectasis with asthma was 69. 7%, and that in the group of bronchiectasis with rhinitis was 73.9%, and that in bronchiectasis alone group was 24. 6%. The positive rate of SPT in the groups of bronchiectasis with asthma and bronchiectasis with rhinitis were significantly higher than that in bronchiectasis alone group（x^2 = 29. 458, X^2 = 37. 562, all P 〈0. 01）. There was no significant difference in the positive rate of SPT between the group of bronchiectasis with asthma and the group of bronchiectasis with rhinitis（x^2 = 0. 344, P 〉0.05）. Conclusion]The incidence rate of bronchiectasis accompanying with allergic diseases increases ob- viously. Allergy reaction may play an important role in the genesis and development of bronchiectasis.