浅表性大疱型坏疽性脓皮病

报告1例浅表性大疱型坏疽性脓皮病。患者女，58岁。四肢红斑、水疱、溃疡伴疼痛9d入院。组织病理表现为表皮内有一大脓疱，脓疱两侧表皮内有较多中性粒细胞侵入，两侧表皮有明显细胞间及细胞内水肿，真皮浅层及中层有弥漫性中性粒细胞浸润，有明显核尘，核碎裂，真皮胶原纤维间水肿，皮下组织有部分区域出血。类似于典型坏疽性脓皮病，但是在真皮中的位置更表浅。给予小剂量糖皮质激素，米诺环素，雷公藤多苷治疗，2个月后痊愈。

Superficial bullous pyoderma gangrenosum:a case report

A case of superficial bullous pyoderma gangrenosum,a variant of pyoderma gangrenosum(PG),is reported. The patient was a 58-year-old female,who presented with painful erythema,bullae,and ulcer on the extremities for 9 days,and was hospitalized. Histopathology showed a large intraepidermal pustule with obvious neutrophilic infiltration,intercellular and intracellular edema in the periphery. There were diffuse neutrophilic infiltration,with nuclear dusts and the edema between collagen fibers in the middle and ...