正常孕妇血常规参考值范围的序贯性测定 |
| |
引用本文: | 叶蕾,陈岚,杜泽丽,蒋冬梅,江咏梅,旷凌寒,张鸽.正常孕妇血常规参考值范围的序贯性测定[J].华西医学,2009,24(2):403-405. |
| |
作者姓名: | 叶蕾 陈岚 杜泽丽 蒋冬梅 江咏梅 旷凌寒 张鸽 |
| |
作者单位: | 四川大学华西第二医院检验科,四川成都,610041
|
| |
摘 要: | 目的:了解正常妊娠妇女常用血常规指标的变化,建立其参考值范围。方法:分别在早孕(孕10~14周)、中孕(孕20~24周)、晚孕(孕30~34周)及产后(产后12周)四个时期序贯性测定120例正常妊娠妇女血常规指标:红细胞(RBC)、血红蛋白(HB)、红细胞压积(HCT)、血小板(PLT)、白细胞(WBC),并建立参考值范围。同期选取53例健康体检非孕者为对照。结果:RBC、HCT早、中、晚孕相对于正常对照均降低(P〈O.01)。HB在孕期降低,中、晚孕降低较明显,相对于正常对照差异有统计学意义(P〈0.01)。PLT早、中孕降低不明显(P〉0.05),到晚孕期相对于正常对照降低差异有统计学意义(P〈0.05)。WBC在妊娠四期相对于正常对照均升高(P〈O.01)。结论:血常规各项指标随孕期发展均产生不同程度的变化,从该序惯性研究中得出了正常妊娠妇女的5个血常规指标水平的参考值范围,该参考值范围可以用于评估正常妊娠妇女的孕期健康水平。
|
关 键 词: | 正常妊娠 孕周相关 血常规指标 参考值范围 |
Reference Intervals for Haematological Variables during Normal Pregnancy |
| |
Institution: | YE Lei,CHEN Lan,DU Ze-li,et al. (Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041 ,China) |
| |
Abstract: | Objective:To study the trends and reference intervals for haematological variables during normal pregnancy and postpartum. Methods: The series comprised 120 women with a normal pregnancy and a normal delivery. Blood samples were obtained at 10 - 14 W, 20- 24 W, 30-34 W gestation and at 12 W postpartum. The following indicators were analyzed : red blood cell (RBC), hemoglobin (HB), hematocrit (HCT), platelet (PLT) and white blood cell (WBC). Reference values were calculated as mean±1. 96 × SD. Simultaneously, 53 healthy unpregnant women were chosen as controls. Results: Compared to normal ranges, RBC and H CT values declined during pregnancy (P〈0.01 ), while WBC value increased (P〈0.01). HB fell down in the whole process of pregnancy (P〈0.01). PLT did not show a clear change at 10-14 W and 20-24 W (P〉0.05) ,but it declined significantly at 30-34 W and postpartum (P〈0.05). Conclusion:The characteristic changes occur in haematological indices during pregnancy and postpartum. The resuits may be used as reference values in the assessment of health status of pregnant women. |
| |
Keywords: | normal pregnancy gestational week related haematological variables reference intervals |
本文献已被 维普 万方数据 等数据库收录! |
|