| 早期空肠内营养联合高容量血液滤过治疗重症急性胰腺炎 |
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| 引用本文： | 李方,肖宏,曾钧发,桂培根. 早期空肠内营养联合高容量血液滤过治疗重症急性胰腺炎[J]. 中国实用医药, 2010, 5(9): 13-14 |
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| 作者姓名： | 李方 肖宏 曾钧发 桂培根 |
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| 作者单位： | 南华大学附属第二医院,421001 |
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| 摘 要： | 目的观察经鼻空肠管行肠内营养（EN）联合高容量血液滤过治疗重症急性胰腺炎（SAP）的临床疗效。方法回顾分析2006年6月至2008年12月本科收治的SAP患者72例。其中40例（对照组）行连续高容量血液滤过及全静脉营养（TPN）;32例（治疗组）在连续高容量血液滤过治疗及经鼻空肠管肠内营养（EN）治疗,观察两组患者生命体征,测定血液TNF-α、IL-6及内毒素的含量。结果两组治疗后APACHEⅡ评分,血液细胞因子含量均明显降低,治疗前后差异有统计学意义（P〈0.05）;对照组内毒素的含量于治疗开始后逐渐升高,而治疗组内毒素的含量在治疗短时间内升高后逐渐降低,组间差异有统计学意义P〈0.05。结论血液滤过能降低血液炎症介质及细胞因子,经鼻空肠管肠内营养能较好地改善胃肠功能,降低血液内毒素含量,两者早期联合应用能提高SAP的临床疗效。
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| 关 键 词： | 胰腺炎 空肠内营养 连续血液滤过 生大黄 内毒素 |
Teatment with early jejunum nutrition combined with high-volume hemofiltration for patients with severe acute pancreatitis |
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| LI Fang,XIAO Hong,CENG Jun-fa,et al.. Teatment with early jejunum nutrition combined with high-volume hemofiltration for patients with severe acute pancreatitis[J]. China Practical Medical, 2010, 5(9): 13-14 |
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| Authors: | LI Fang XIAO Hong CENG Jun-fa et al. |
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| Affiliation: | LI Fang,XIAO Hong,CENG Jun-fa,et al.The Second Affiliated Hospital of South University of China,Hengyang 421001,China |
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| Abstract: | Objective To investigate the effect of early treatment with a combination of early jejunum nutrition and high-volume hemofiltration for patients with severe acute pancreatitis.Methods We retrospectively analyzed the 72 SAP patients,who were treated in our department between June 2006 and December 2008.40 patients(control group)received high-volume hemofiltration and total parenteral nutrition and the other 32 patients(treatment group)received both early jejunum nutrition and high-volume hemofiltration.The v... |
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| Keywords: | Pancreatitis Jejunum nutrition Continuous hemofiltration Rhubarb Plasma endotoxin |
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