胆管黏液腺癌的诊断与治疗

目的分析胆管黏液腺癌的诊断与治疗。方法回顾分析郑州大学人民医院2015年5月至2017年7月收治的6例胆管黏液腺癌病人的临床病理资料,总结其临床病理学特征、诊断及治疗方式,结合国内外文献分析阐述。结果本组6例病人,男性2例,女性4例,年龄38~67岁,平均52.3岁。主要症状为腹痛、发热、黄疸。CT及MRI均提示肝内外胆管不同程度扩张,磁共振胰胆管成像(MRCP)显示肿瘤在高信号的胆汁衬托下呈结节状、乳头状、斑片状等相对低信号表现。6例病人均行手术治疗,术后顺利出院。随访时间1~27个月,中位随访时间18个月,均存活。结论胆管黏液腺癌术前诊断较为困难,MRCP具有明显的优势,根治性手术切除是最有效的治疗手段。

Diagnosis and treatment of mucinous cholangiocarcinoma

Objective To analyze the diagnosis and treatment of mucinous cholangiocarcinoma (MCC).Methods A retrospective study was made on the clinicopathological features of 6 MCC patients in Zhengzhou University People's Hospital from May 2015 to July 2017.The clinical and pathological features,diagnosis and treatment of these 6 cases of MCC were summarized,and the relative literatures were reviewed.Results There were 2 males and 4 females with age ranging from 38 to 67 years old (average of 52.3 years old).The common symptoms were abdominal pain,fever and jaundice.Intra-and extra-hepatic bile duct dilation to varying degrees was seen in CT and MRI scans.Nodal,mammillary,plaque relative low signal mass was displayed in MRCP scan.Six patients were discharged after surgery.At a median follow up for 18 months (range 1 to 27 months),all patients survived.Conclusions The diagnosis of MCC is very difficult preoperatively.MRCP has obvious advantages compared with other methods.Radical surgical resection is the most effective method for MCC patients.