| Modulation of cellular and humoral immune responses to anHIV-1 DNA vaccine by interleukin-12 and interleukin-18 DNA immunization |
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| 引用本文： | 孙永涛,王福祥,孙永年,徐哲,王临旭,刘娟,白雪帆,黄长形. Modulation of cellular and humoral immune responses to anHIV-1 DNA vaccine by interleukin-12 and interleukin-18 DNA immunization[J]. 中国人民解放军军医大学学报, 2004, 19(4): 205-210 |
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| 作者姓名： | 孙永涛 王福祥 孙永年 徐哲 王临旭 刘娟 白雪帆 黄长形 |
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| 作者单位： | Center of Diagnosis and Treatment for Infectious Diseases of PLA，Tangdu Hospital，Fourth Military Medical University，Xi'an 710038，China，Department of Infections Diseases，The First Affiliated Hospital of Harbin Medical University，Harbin 150086，Heilongjiang Province，China，Center of Diagnosis and Treatment for Infectious Diseases of PLA，Tangdu Hospital，Fourth Military Medical University，Xi'an 710038，China，Center of Diagnosis and Treatment for Infectious Diseases of PLA，Tangdu Hospital，Fourth Military Medical University，Xi'an 710038，China，Center of Diagnosis and Treatment for Infectious Diseases of PLA，Tangdu Hospital，Fourth Military Medical University，Xi'an 710038，China，Center of Diagnosis and Treatment for Infectious Diseases of PLA，Tangdu Hospital，Fourth Military Medical University，Xi'an 710038，China，Center of Diagnosis and Treatment for Infectious Diseases of PLA，Tangdu Hospital，Fourth Military Medical University，Xi'an 710038，China，Center of Diagnosis and Treatment for Infectious Diseases of PLA，Tangdu Hospital，Fourth Military Medical University，Xi'an 710038，China |
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| 摘 要： | Thereismountingevidencethattheinductionofstrongmucosalandcell mediatedimmuneresponsesarekeyelementstoconsiderinconstructingefficaciousHIV 1vac cine .TherapeuticvaccinesthatinducehighlevelsofCTLspecifictoHIVarecurrentlybeingdevelopedworldwide .NucleicacidimmunizationisanewvaccinationtechniquewhichdeliversDNAconstructsencodingaspecificimmuno genintothehost[1] .InadditiontotheabilityoftheDNAvaccinetoinducebothantigen specificcellularandhumor alimmuneresponses ,thistechniquehasthepotentialto…
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| 关 键 词： | 细胞调制 体液免疫反应 HIV-1 DNA 疫苗 白细胞间介素-12 白细胞间介素-18 |
Modulation of cellular and humoral immune responses to anHIV-1 DNA vaccine by interleukin-12 and interleukin-18 DNA immunization |
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| SUN Yong-tao ,WANG Fu-xiang ,SUN Yong-nian ,XU Zhe ,WANG Lin-xu ,LIU Juan ,BAI Xue-fan ,HUANG Chang-xing Center of Diagnosis and Treatment for Infectious Diseases of PLA,Tangdu Hospital,Fourth Military Medical University,Xi'an ,China. Modulation of cellular and humoral immune responses to anHIV-1 DNA vaccine by interleukin-12 and interleukin-18 DNA immunization[J]. Journal of Medical Colleges of PLA(China), 2004, 19(4): 205-210 |
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| Authors: | SUN Yong-tao WANG Fu-xiang SUN Yong-nian XU Zhe WANG Lin-xu LIU Juan BAI Xue-fan HUANG Chang-xing Center of Diagnosis Treatment for Infectious Diseases of PLA Tangdu Hospital Fourth Military Medical University Xi'an China |
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| Affiliation: | SUN Yong-tao 1,WANG Fu-xiang 2,SUN Yong-nian 1,XU Zhe 1,WANG Lin-xu 1,LIU Juan 1,BAI Xue-fan 1,HUANG Chang-xing 1 1Center of Diagnosis and Treatment for Infectious Diseases of PLA,Tangdu Hospital,Fourth Military Medical University,Xi'an 710038,China 2Department of Infections Diseases,The First Affiliated Hospital of Harbin Medical University,Harbin 150086,Heilongjiang Province,China |
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| Abstract: | |
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| Keywords: | HIV DNA vaccination interleukin-12 interleukin-18 |
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