| 小金丸加减抗肿瘤的实验研究 |
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| 引用本文： | 周阿高,肖碧兰.小金丸加减抗肿瘤的实验研究[J].上海交通大学学报(医学版),1990,10(3):185-188. |
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| 作者姓名： | 周阿高 肖碧兰 |
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| 作者单位： | 上海第二医科大学中医学教研室，上海第二医科大学中医学教研室，河南省新乡市中医院，上海第二医科大学中医学教研室，上海第二医科大学药理学教研室，上海市消化疾病研究所 进修医师 |
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| 摘 要： | 本实验用小金丸加减治疗S_(180)小鼠。主要观察指标有全血粘度和瘤重。结果显示:小金丸加减能明显降低S_(180)小鼠的全血粘度,显著抑制肿瘤生长,而对小鼠体重增长无明显抑制作用。提示小金丸加减具有良好的改善血瘀状态和抑制肿瘤生长的作用,且有副作用小的优点。这为血瘀是肿瘤的主要病机之一的理论提供了实验依据。
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| 关 键 词： | 小金丸 抗肿瘤 |
Experimental Investigation on the Anti-cancer Effect of Modified Xiaojin Pellet |
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| Zhou Agao,et al.Experimental Investigation on the Anti-cancer Effect of Modified Xiaojin Pellet[J].Journal of Shanghai Jiaotong University:Medical Science,1990,10(3):185-188. |
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| Authors: | Zhou Agao |
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| Institution: | Zhou Agao,et al Department of Traditional Chinese Medicine,Shanghai Second Medical University,Shanghai |
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| Abstract: | Since blood stasis is one of the pathogenetic features in cancer, experiment was made on S180 mice with disordered microcirculation and increase of blood viscosity. After treatment with modified Xiaojin pellet, blood viscosity was much lower than in controls (P<0.05), cancer growth was inhibited markedly while the increase in body weight was unaffected (P<0.05). Unlike 5-Fu, Xiaoiin pellet oaused very little side effect. |
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