晚发性维生素K缺乏致颅内出血危险因素分析

目的探讨晚发性维生素K缺乏致颅内出血发病的危险因素。方法对57例晚发性维生素K缺乏致颅内出血进行了总结,并应用非条件Logistic回归分析,对8项可能的危险因素进行分析。结果晚发性维生素K缺乏致颅内出血发病危险模型Y=-4.405 1.652X1 2.418X2 2.076X3 2.782X7 1.617X8,X1=性别,X2=年龄,X3=喂养方式,X7=CMV感染,X8=肝功能异常。结论男性、年龄<3个月、纯母乳喂养、有CMV感染、肝功能异常者易发生晚发性维生素K缺乏致颅内出血。

Analysis of risk factors in intracranial hemorrhage of late vitamin K deficiency

Objective To investigate the risk factors of onset of intracranial hemorrhage induced by late vitamin K deficiency.Methods Fifty-seven children with intracranial hemorrhage induced by late vitamin K deficiency were retrospectivly reviewed and eight possible risk factors were analyzed by Logistic regression method.Results The onset hazard model of intracranial hemorrhage of late vitamin K deficiency was valued as:Y=-4.405 1.652X_1 2.418X_2 2.076X_3 2.782X_7 1.617X_8,among them X_1 was defined as sex,X_2 was defined as age,X_3 was defined as feeding mode,X_7 was defined as infection of cytomegalovirus,X_8 was defined as abnormal hepatic function.Conclusion Children of male,with age less than 3 year,only feeded with woman milk,with infection of cytomegalovirus,with abnormal hepatic function were easily to take place intracranial hemorrhage of late vitamin K deficiency.