| 白血病抑制因子在妊娠输卵管黏膜中的表达 |
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| 引用本文： | 熊超,周东旭,刘帆,朱成成,何艳君,晏长荣. 白血病抑制因子在妊娠输卵管黏膜中的表达[J]. 解剖学研究, 2013, 35(1): 40-42 |
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| 作者姓名： | 熊超 周东旭 刘帆 朱成成 何艳君 晏长荣 |
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| 作者单位： | 湖北医药学院第一临床学院,湖北十堰,442000 |
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| 摘 要： | 目的探讨白血病抑制因子(LIF)与输卵管妊娠的关系。方法选择输卵管妊娠组25例、正常输卵管组28例及正常宫内早孕组30例,采用免疫组织化学染色技术及半定量病理图像分析系统检测输卵管妊娠黏膜组织、正常输卵管黏膜组织及正常宫内早孕组子宫蜕膜组织中LIF的表达。结果 LIF阳性表达在正常宫内早孕组最高,在输卵管妊娠组中较高,在正常输卵管组中最低,三组两两比较差异均有有统计学意义(P<0.05)。结论 LIF可能参与了输卵管妊娠发病过程,且与输卵管妊娠缺乏蜕膜化反应有关。
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| 关 键 词： | 输卵管妊娠 白血病抑制因子(LIF) 免疫组织化学 |
Expression of leukemia inhibitory factor in human oviductal mucosa of tubal ectopic pregnancy |
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| XIONG chao , ZHOU Dong-xu , LIU Fan , ZHU Cheng-cheng , HE Yan-Jun , YAN Zhang-rong. Expression of leukemia inhibitory factor in human oviductal mucosa of tubal ectopic pregnancy[J]. Anatomy Research, 2013, 35(1): 40-42 |
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| Authors: | XIONG chao ZHOU Dong-xu LIU Fan ZHU Cheng-cheng HE Yan-Jun YAN Zhang-rong |
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| Affiliation: | .Anesthesia Major,First Clinical College,Hubei University of Medicine,Shiyan 442000,China |
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| Abstract: | Objective To explore the relationship between leukemia inhibitory factor gene(LIF) and tubal ectopic pregnancy.Methods Expression of LIF was detected by immunohistochemistry in oviductal mucosa in tubal ectopic pregnancy group(n=25),in oviductal mucosa in normal oviduct group(n=28) and in decidua tissues in early pregnancy group(n=30),and the data were analyzed by semi-quantity pathologic image analysis.Results The positive expression of LIF in tubal ectopic pregnancy group was significantly stronger than that in normal human oviduct group(P<0.05),but was significantly weaker than that in early pregnancy group(P<0.05).Conclusion LIF may be involved in the tubal ectopic pregnancy,and be correlated with indistinct decidualization of tubal ectopic pregnancy. |
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| Keywords: | Tubal ectopic pregnancy Leukemia inhibitory factor(LIF) Immunohistochemistry |
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