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触觉刺激三叉神经上颌支面部支配区的功能性MRI研究
引用本文:李家,刘洪臣,李科,金真,朱霞.触觉刺激三叉神经上颌支面部支配区的功能性MRI研究[J].口腔颌面外科杂志,2013,23(2):98-100.
作者姓名:李家  刘洪臣  李科  金真  朱霞
作者单位:李家 (同济大学口腔医学院生物医学及转化实验室,上海202072;解放军总医院口腔医学院研究所,北京 100083); 刘洪臣 (解放军总医院口腔医学院研究所,北京,100083); 李科 (解放军306医院放射科,北京,100101); 金真 (解放军306医院放射科,北京,100101); 朱霞 (同济大学口腔医学院生物医学及转化实验室,上海,202072);
基金项目:国家自然科学基金资助项目(30772450)
摘    要:目的:观察触觉刺激三叉神经上颌支(简称V2)面部支配区引起的大脑中枢反应区。方法 :选取8名健康志愿者,用棉签刺激右侧面部三叉神经上颌支的支配区,采用触觉刺激减静息的组块设计方法,采集全脑血氧水平依赖对比的功能性MRI扫描数据。结果:脑激活区为左侧初级躯体感觉皮质(BA3)、岛叶/SII、BA22、BA45,右侧BA40、BA9、BA38、BA41。结论:对侧初级躯体感觉皮质、岛叶/SII和颞上回,同侧中央后回、颞下回和颞横回及双侧前额皮质是面部V2区触觉刺激激活的脑部功能区。

关 键 词:颌面部  触觉  大脑皮质  功能性磁共振成像(fMRI)

Brain Activity and Facial Tactile in Trigeminal Maxillary Division: An Functional MRI Study
LI Jia,LIU Hong-chen,LI Ke,JIN Zhen,ZHU Xia.Brain Activity and Facial Tactile in Trigeminal Maxillary Division: An Functional MRI Study[J].Chinese Journal of Oral and Maxillofacial Surgery,2013,23(2):98-100.
Authors:LI Jia  LIU Hong-chen  LI Ke  JIN Zhen  ZHU Xia
Institution:1(1.Laboratory of Oral Biomedical Science and Translational Medicine,School of Stomatology,Tongji University,Shanghai,200072;2.Department of Stomatology,The PLA General Hospital,Beijing 100853;3.Department of Radiology,PLA 306 Hospital,Beijing 100101,China)
Abstract:Objective:To evaluate the brain cortical response to facial tactile in maxillary trigeminal division.Methods:8 healthy volunteers participated in the study.Cotton-tipped swab stimuli was applied to right side of face in maxillary trigeminal division,and block designed BOLD functional MRI scan covering the whole brain was carried out.Results:Increased BOLD signals during tactile stimulation were found in left SI(BA3),insula/SII,Brodman's area 22,45,and right Brodman's area 40,9,38,41.Conclusion:Tactile stimuli activated contralateral primary,secondary somatosensory cortex,superior temporal gyrus,ipsilateral postcentral gyrus,inferior temporal gyrus,transverse temporal gyrus,bilateral prefrontal cortex.
Keywords:maxillofacial region  tactile  cortex  functional MRI(fMRI)
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