| 胶体果胶铋胶囊联合自拟益气肠化方改善萎缩性胃炎伴肠上皮化生患者胃功能指标的效果 |
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| 引用本文： | 李阅桥,徐永居. 胶体果胶铋胶囊联合自拟益气肠化方改善萎缩性胃炎伴肠上皮化生患者胃功能指标的效果[J]. 实用临床医药杂志, 2019, 23(12): 75-78,82 |
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| 作者姓名： | 李阅桥 徐永居 |
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| 作者单位： | 江苏省苏北人民医院药学部,江苏扬州,225001;江苏省苏北人民医院消化内科,江苏扬州,225001 |
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| 摘 要： | 目的探讨胶体果胶铋胶囊联合自拟益气肠化方改善慢性萎缩性胃炎(CAG)伴肠上皮化生(IM)患者的效果。方法选取CAG伴IM患者80例,随机分为联合组与对照组,每组40例。对照组给予胶体果胶铋胶囊治疗,联合组给予胶体果胶铋胶囊联合自拟益气肠化方治疗。比较2组治疗后的临床疗效、中医症状积分、胃黏膜病理积分以及胃功能指标[胃蛋白酶原Ⅰ(PGⅠ)、胃蛋白酶原Ⅱ(PGⅡ)]。结果联合组总有效率显著高于对照组(P<0.05)。治疗后,2组患者中医症状积分均较治疗前显著降低,且联合组显著低于对照组(P<0.05)。治疗后,2组腺体萎缩、肠上皮化生积分均较治疗前显著下降(P<0.05),且联合组显著低于对照组(P<0.05)。治疗后,2组患者PGⅠ水平较治疗前显著升高(P<0.05),PGⅡ水平显著下降(P<0.05),且联合组PGI水平显著高于对照组(P<0.05),PGⅡ水平显著低于对照组(P<0.05)。结论胶体果胶铋胶囊联合自拟益气肠化方治疗CAG伴IM患者的疗效确切,能显著改善患者的胃黏膜病理表现,有效调节胃蛋白酶原的水平。
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| 关 键 词： | 胶体果胶铋胶囊 自拟益气肠化方 慢性萎缩性胃炎 肠上皮化生 胃蛋白酶原 病理 |
Effect evaluation of colloidal bismuth pectin capsules combined with self-made Yiqi Changhua Regime on improvement of gastric function indexes in chronic atrophic gastritis patients with intestinal metaplasia |
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| LI Yueqiao,XU Yongju. Effect evaluation of colloidal bismuth pectin capsules combined with self-made Yiqi Changhua Regime on improvement of gastric function indexes in chronic atrophic gastritis patients with intestinal metaplasia[J]. Journal of Clinical Medicine in Practice, 2019, 23(12): 75-78,82 |
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| Authors: | LI Yueqiao XU Yongju |
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| Affiliation: | (Department of Pharmacy,Subei People′s Hospital,Yangzhou,Jiangsu,225001;Department of Digestion,Subei People′s Hospital,Yangzhou,Jiangsu,225001) |
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| Abstract: | LI Yueqiao;XU Yongju(Department of Pharmacy,Subei People′s Hospital,Yangzhou,Jiangsu,225001;Department of Digestion,Subei People′s Hospital,Yangzhou,Jiangsu,225001) |
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| Keywords: | colloidal bismuth pectin capsules self-made Yiqi Changhua Regime chronic atrophic gastritis intestinal metaplasia pepsinogen pathology |
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