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柿蒂总鞣质的抗氧化活性研究
引用本文:周本宏,魏嫣,张琛霞,沈恒,邱振鹏.柿蒂总鞣质的抗氧化活性研究[J].广东药学院学报,2010,26(6):599-601.
作者姓名:周本宏  魏嫣  张琛霞  沈恒  邱振鹏
作者单位:[1]武汉大学人民医院,湖北武汉430060 [2]武汉大学药学院,湖北武汉430072
摘    要:目的研究柿蒂总鞣质提取物的抗氧化活性。方法从柿蒂总鞣质提取物清除羟基自由基(·OH)、超氧离子自由基(O2·-),抑制脂质体过氧化活性及还原力等方面进行研究。结果柿蒂总鞣质具有较强的还原力,对·OH的清除能力较强,对O2·-的清除能力较弱,能显著性抑制脂质过氧化。结论柿蒂总鞣质是一种抗氧化功能较好的活性物质,具有良好的开发前景。

关 键 词:柿蒂  鞣质  抗氧化活性

Study on antioxidant activity of total tannins from Persimmon calyx
ZHOU Ben-hong,WEI Yan,ZHANG Chen-xia,SHEN Heng,QIU Zhen-peng.Study on antioxidant activity of total tannins from Persimmon calyx[J].Academic Journal of Guangdong College of Pharmacy,2010,26(6):599-601.
Authors:ZHOU Ben-hong  WEI Yan  ZHANG Chen-xia  SHEN Heng  QIU Zhen-peng
Institution:1.Department of Pharmacy,Renmin Hospital of Wuhan University,Wuhan,Hubei 430060,China;2.College of Pharmacy,Wuhan University,Wuhan,Hubei 430072)
Abstract:Objective To investigate the antioxidant activity of total tannins from Persimmon calyx in vitro.Methods The antioxidant activity of total tannins from Persimmon calyx was analyzed with different assays,such as hydroxyl radical scavenging assay,superoxide radical scavenging assay,anti-lipid peroxidation and reducing capability.Results Strong reducing capability was observed,as well as significant scavenging effect to hydroxyl radicals and peroxidation inhibiting effect for the lipids,but weak superoxide radical scavenging activity.Conclusion Total tannins from Persimmon calyx has good antioxidant activity,which appears to be a promising natural antioxidant.
Keywords:Persimmon Calyx  tannin  antioxidant activity
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