Four cases of follicular lymphoma with t(14;18)(q32;q21) and t(3;4)(q27;p13) with LAZ3 (BCL6) rearrangement. |
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| Authors: | A Daudignon H Bisiau F Le Baron J L La? M Wetterwald S Galiègue-Zouitina P Morel P Duthilleul |
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| Affiliation: | Département d'Hématologie-Immunologie-Cytogénétique, Centre Hospitalier de Valenciennes, France. |
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| Abstract: | We report four cases of follicular lymphoma with both t(14;18)(q32;q21) and the newly characterized t(3;4)(q27;p13). Molecular investigation confirmed LAZ3 (BCL6) rearrangement for all patients. The 3q27 aberrations have been rarely described in low-grade lymphomas and may represent secondary events whose implication remains to be elucidated. |
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