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针刺不同经穴对正常人事件相关电位P3a和P3b的影响
引用本文:蔡荣林,胡玲,吴子建,汪克明,何璐,周逸平,赵仑,胡吴斌.针刺不同经穴对正常人事件相关电位P3a和P3b的影响[J].中西医结合学报,2012,10(1):48-53.
作者姓名:蔡荣林  胡玲  吴子建  汪克明  何璐  周逸平  赵仑  胡吴斌
作者单位:1. 安徽中医学院针灸经络研究所,安徽合肥,230038
2. 北京飞宇星科技有限公司EEG/ERP实验室,北京,100097
基金项目:国家自然科学基金资助项目
摘    要:目的:探讨针刺不同经脉穴位对大脑注意功能的影响,为进一步揭示针刺心经经穴神门效应的脑功能与脑整合机制奠定基础。方法:选择10名健康青年大学生作为试验对象,采用视觉新奇刺激和靶刺激诱导P3a和P3b电位,采用Neuroscan事件相关电位系统,选择测量时间窗口为330~430ms和400~600ms,观察手针心经神门穴与肺经太渊穴前后P300强度分布的变化。结果:针刺神门或太渊后P3a、P3b的波幅均显著降低,但降低的程度受针刺穴位的调控和影响;在电极FCz记录位置,针刺神门引起更大程度的P3a波幅的降低(P〈0.05)。结论:手针神门或太渊穴均能影响大脑的注意功能,针刺神门对人体大脑注意功能的影响更大。

关 键 词:针刺穴位  事件相关电位  P300  神门  太渊  人类实验

Effects of acupuncture at Shenmen (HT7) or Taiyuan (LU9) on P3a and P3b of event-related potentials in healthy young adults
Rong-lin Cai , Ling Hu , Zi-jian Wu , Ke-ming Wang , Lu He , Yi-ping Zhou , Lun Zhao , Wu-bin Hu.Effects of acupuncture at Shenmen (HT7) or Taiyuan (LU9) on P3a and P3b of event-related potentials in healthy young adults[J].Journal of Chinese Integrative Medicine,2012,10(1):48-53.
Authors:Rong-lin Cai  Ling Hu  Zi-jian Wu  Ke-ming Wang  Lu He  Yi-ping Zhou  Lun Zhao  Wu-bin Hu
Institution:Institute of Acupuncture and Moxibustion, Anhui University of Traditional Chinese Medicine, Hefei, Anhui Province, China.
Abstract:OBJECTIVE: To investigate the effects of manual acupuncture at Shenmen (HT7) or Taiyuan (LU9) on the attention function of the brain, and to lay an experimental foundation for researching brain function and integration mechanisms of the human brain in relation to acupuncture stimulation. METHODS: Ten healthy young college students were selected as experimental subjects. P3a and P3b potentials were induced by novel stimulation and target stimulation with vision and were observed using Neuroscan event-related potentials system at time windows of ms 330-430 or 400-600 ms for observing the change of intensity distribution of P300 after manual acupuncture at HT7 or LU9. RESULTS: The amplitude of P3a and P3b decreased significantly after manual acupuncture at HT7 or LU9, but the degree of decreases affected by the acupoints was different. The decrease of the amplitude of P3a due to acupuncture at HT7 was more significant than acupuncture at LU9 (P0.05). CONCLUSION: The attention function of the brain is affected by manual acupuncture at HT7 or LU9 and manual acupuncture at HT7 has a greater influence on the attention function of the brain.
Keywords:acupuncture points  event-related potentials  P300  Shenmen (HT7)  Taiyuan (LU9)  human experimentation
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