| 香菇多糖胶囊抗突变作用的实验研究 |
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| 引用本文： | 陈冠敏,林升清,黄宗锈,陈纫雄,何玲,姜瑞钗.香菇多糖胶囊抗突变作用的实验研究[J].癌变．畸变．突变,2000,12(2):105-108. |
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| 作者姓名： | 陈冠敏 林升清 黄宗锈 陈纫雄 何玲 姜瑞钗 |
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| 作者单位： | 福建省卫生防疫站,福建福州 350001 |
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| 摘 要： | 目的与方法：本文采用Ａｍｅｓ试验及活体小鼠骨髓嗜多染红细胞微核试验方法，对香菇交囊进行抗突变试验，结果：香菇多糖胶囊各剂量级天加与不加Ｓ９的条件下，均能抑制由２－氨基芴等阳笥物引起的ＴＡ９８、ＴＡ１００同变菌落数的增加；抑制由环磷酰胺引 小鼠微核率的增加，抑制率在４５．３２％￣６４．７２％。结论：香菇多糖胶囊具有一定的抗突变作用。
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| 关 键 词： | 香菇多糖 抗突变作用 Ames试验 微核试验 |
| 文章编号： | 1004-616(2000)02-0105-03 |
| 修稿时间： | 1999年6月16日 |
STUDY ON THE ANTIMUTAGENICITY OF LENTINAN |
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| Abstract: | Purpose and Methods: The effect on antimutation of Lentinan was studied by Ames test and micronucleus test with polychromatic erythrocyte(PCE) of mouse bone marrow in vivo. Results: The rusults show that the increasing of the number of bacteria in different dose groups can be inhibited by Lentinan. Lentinan inhibited the increasing of micronucleus rate and the inhibition rate is between 45.32% and 64.72%. Conclusion: It has been observed that Lentinan possess significant antimutagenic effect. |
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| Keywords: | Lentinan antimutagenicity Ames test micronucleus test |
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