急性一氧化碳中毒迟发性脑病预后影响因素分析

目的 通过收集急性一氧化碳中毒迟发性脑病(DEACMP)患者的临床资料,分析影响其预后的因素.方法 回顾性分析2003年2月至2007年5月在我科住院的35例DEACMP患者临床资料,6个月～3年后随访其恢复情况,总结出性别、年龄、基础疾病、吸烟、急性期是否高压氧(HBO)治疗、昏迷时间、中毒时间、假愈期、最重时日常生活能力量表(ADL)评分、并发症、HBO治疗次数及神经节苷脂(GM-1)的应用等12个可能影响此病预后的因素.用SPSS10.0软件对数据作X2检验.结果 中毒时间、最重时ADL评分、并发症、HBO治疗次数对预后有一定影响,其中最重时ADL评分及并发症对预后有较大影响;而其余因素对预后影响不大.结论 中毒时间越长、最重时ADL评分越低及病程中出现并发症的患者预后较差,疾病治疗过程中应注意加强患者的护理,减少并发症的发生,并积极进行HBO治疗.

Prognostic factors in delayed encephalopathy after acute carbon monoxide poisoning

Objective To explore the prognostic factors of delayed encephalopathy after carbon monoxide poisoning( DEACMP). Methods Thirty-five patients diagnosed as DEACMP in our hospital from February 2003 to May 2007 were observed. After follow-up visiting, factors of age,sex,fundament diseases, smoking,hyperbaric oxygen treatment(HBOT) in acute stage,unconsciousness time,intoxication time,fake-cure stage, danger-activity of daily living scale (ADL) scores, complications, HBOT frequency and ganglioside administration were analyzed, respectively. Chi-Square test was used to analyse those data by SPSS10. 0 software. Results Intoxication time, danger-ADL scores, complications and HBOT frequency had effected on the recovery of DEACMP( P <0. 05 ) , especially danger-ADL scores and complications(P < 0. 01). The other factors did not have significant difference(P>0.05). Conclusions Longer intoxication time,less danger-ADL scores and more complications lead to slower recovery. Nursing care and HBO treatment should be reinforced.