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Mitochondrial genome depletion dysregulates bile acid- and paracetamol-induced expression of the transporters Mdr1, Mrp1 and Mrp4 in liver cells |
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| Authors: | Perez M J Gonzalez-Sanchez E Gonzalez-Loyola A Gonzalez-Buitrago J M Marin J J G |
| Institution: | 1Research Unit, University Hospital, Salamanca, 37007 Salamanca, Spain;2Instituto de Estudios de Ciencias de la Salud de Castilla y León, Spain;3Laboratory of Experimental Hepatology and Drug Targeting, CIBERehd, University of Salamanca, 37007 Salamanca, Spain |
| Abstract: | |
| Keywords: | ABC proteins paracetamol (acetaminophen) bile acid cholestasis drug toxicity liver mitochondria multidrug resistance retrograde control rho cells |
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